LKS MEDICAL FACULTY
| Researcher : Boheler KR |
| Project Title: | Mechanistic Study of Vascular Ehlers-Danlos Syndrome using Induced Pluripotent Stem Cells derived from Humans with COL3A1 Mutations |
| Investigator(s): | Boheler KR, Li RA, Chan CWY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2014 |
| Completion Date: | 10/2017 |
| Project Title: | Establishing an internationally competitive Stem Cell Biotech Cluster in HK: Bioartificial Human Hearts |
| Investigator(s): | Boheler KR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 2) |
| Start Date: | 01/2015 |
| Project Title: | Establishing an Internationally Competitive Stem Cell Biotech Cluster in HK: Bioartificial Human Hearts |
| Investigator(s): | Boheler KR, Li RA |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2015 |
| Project Title: | STF31 and the Selective Ablation of Tumorigenic Human Pluripotent Stem Cells from Differentiated Cells Destined for Regenerative Medicine |
| Investigator(s): | Boheler KR, Lo ACY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Completion Date: | 12/2018 |
| Project Title: | Eliminating barriers to the use of GMP-qualified human pluripotent stem cell-derived midbrain dopaminergic neurons for cell based therapies |
| Investigator(s): | Boheler KR, Chan GCF |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 09/2016 |
| List of Research Outputs |
| Chen Y., Huang L., Dai X., Tian Q., Yu M., Agheb M., Chan N.C., Poon N.Y.E., Guo Z., Boheler K.R. and Wu H., Facile formation of a microporous chitosan hydrogel based on self-crosslinking Journal of Materials Chemistry, Journal of Materials Chemistry. 2017, 2017; 5: 9291-9299. |
| Lu J., Boheler K.R., Jiang L., Chan C., Tse W., Keung W.W.Y., Poon N.Y.E., Li R.A. and Yao X., Polycystin-2 Plays an Essential Role in Glucose Starvation-Induced Autophagy in Human Embryonic Stem Cell-Derived Cardiomyocytes, STEM CELLS. 2018, 36: 501-513. |
| Poon N.Y.E., Hao B., Guan D., Li J., Lu J., Yang Y., Wu B., Webb S.E., WU C.M., Miller A.L., Liang Y., Yao X., Wang J., Yan B. and Boheler K.R., Integrated transcriptomics and regulatory network analyses identify microRNA-200c as a novel repressor of differentiation and maturation of human pluripotent stem cell-derived cardiomyocytes, Cardiovascular Research. London, Oxford, 2018, 114: 894-906. |
| Wang J., Cui C., Nan H., Yu Y., Xiao Y., Poon N.Y.E., Yang G., Wang X., Wang C., Li L., Boheler K.R., Ma X., Cheng X., Ni Z. and Chen M., Graphene Sheet-Induced Global Maturation of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells, ACS Applied Materials & Interfaces. 2017, 9: 25929-25940. |
| Yan B., Guan D., Wang C., Wang J.J., He B., Qin J., Boheler K.R., Lu A., Zhang G. and Zhu H., An integrative method to decode regulatory logics in gene transcription, Nature Communications. 2017, 8: 1044. |
| Yan B., Wang P., Wang J.J. and Boheler K.R., Discovery of surface target proteins linking drugs, molecular markers, gene regulation, protein networks and disease by using a web-based platform Targets-search, In: Boheler, Kenneth R., Gundry, Rebekah L, Methods in Molecular Biology. Germany, Springer, 2017, 331-344. |
| Researcher : Chan DTM |
| Project Title: | Gut Microbiota Products in the Pathogenesis of Lupus Nephritis |
| Investigator(s): | Chan DTM, Yung SSY, Yap YHD |
| Department: | Medicine |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 01/2014 |
| Project Title: | The role of Ku70 and Ku80 in the pathogenesis of lupus nephritis |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | The Role of Major Vault Protein in Tubulo-interstitial Injury during Lupus Nephritis |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 06/2015 |
| Project Title: | ASN Kidney Week 2015 Annual Meeting; Serum Acetate and Lipopolysaccharide Levels Correlate with Disease Activity in Patients with Lupus Nephritis |
| Investigator(s): | Chan DTM |
| Department: | Medicine |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2015 |
| Project Title: | The roles of lipopolysaccharide, lipopolysaccharide binding protein and CD14 in the pathogenesis of lupus nephritis |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Project Title: | The role of lysophosphatidic acid in the pathogenesis of lupus nephritis |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2016 |
| Completion Date: | 04/2018 |
| Project Title: | Acetate in the Pathogenesis of Lupus Nephritis |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2017 |
| Project Title: | Role of Major Vault Protein in Fibrotic Processes in Human Mesangial Cells and Proximal Renal Tubular Epithelial Cells |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | Major Vault Protein in Tubulo-interstitial Damage of Chronic Kidney Disease |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2018 |
| Project Title: | The Role of Lipopolysaccharide on CD44-mediated Kidney Inflammation and Fibrosis in Lupus Nephritis |
| Investigator(s): | Chan DTM, Yung SSY |
| Department: | Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2018 |
| List of Research Outputs |
| Yap Y.H.D., Tang C.S.O., Lee P., Tam C., Yam I., Yung S.S.Y. and Chan D.T.M., Relationship between B cell signatures and disease flare in lupus nephritis patients, American Society of Nephrology Kidney Week 2017, New Orleans USA. 2017. |
| Researcher : Chan YC |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Researcher : Chan YS |
| Project Title: | 30th Annual Conference of Society for Neuroscience Expression of N-Methyl-D-Aspartate Receptor Subunits and Induction of c-fos in Otolith Neurons in the Vestibular Nuclei of Postnatal Rats |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2000 |
| Project Title: | 31st Annual Meeting of Society for Neuroscience Expression of Neurotrophin Receptors in Vestibular Nuclei During the Postnatal Development of the Rat |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2001 |
| Project Title: | XXIV Annual Conference of Indian Academy of Neurosciences Development Refinement of Spatial Recognition Circuits |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 12/2006 |
| Project Title: | Role of the thalamus in integrating spatial information and guiding navigation |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2009 |
| Project Title: | Outstanding Research Student Supervisor Award 2009-10 |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Outstanding Research Student Supervisor Award |
| Start Date: | 12/2010 |
| Project Title: | Orexin-induced modulation of activity-dependent synaptic plasticity is critical for the maturation of vestibular circuitry and functions |
| Investigator(s): | Chan YS, Shum DKY, Lai CH |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2015 |
| Project Title: | Semaphorin and perineuronal nets regulate developmental plasticity of central vestibular circuitry |
| Investigator(s): | Chan YS, Shum DKY |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2015 |
| Completion Date: | 03/2018 |
| Project Title: | Neuronal Mechanism of Cholecystokinin-Facilitated Cross-modal Learning and Memory |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2016 |
| Project Title: | Remodeling the sulfation pattern of perineuronal nets in the entorhinal cortical circuit prevents stress-induced decline in learning and memory |
| Investigator(s): | Chan YS, Lai SWC, Shum DKY |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Project Title: | Integration of new neurons into the mature vestibular circuitry requires GABAergic signaling for relevant outcome in behavior |
| Investigator(s): | Chan YS, Lai SWC, Shum DKY |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2016 |
| Project Title: | HKU Centennial Distinguished Chinese Scholars Scheme 2016-17 |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | HKU Centennial Distinguished Chinese Scholars Scheme |
| Start Date: | 09/2016 |
| Project Title: | Selective recruitment of inhibitory interneurons to vestibular microcircuits for distinct behaviour |
| Investigator(s): | Chan YS, Lai SWC, Shum DKY |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2017 |
| Project Title: | Overcoming hurdles in bridging critical nerve gaps to improve post-traumatic nerve regeneration and rehabilitation |
| Investigator(s): | Chan YS, Cai S, Shum DKY, Shea GKH, Tu W |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2018 |
| Project Title: | Strategies to re-open plasticity in the central vestibular circuitry for rescuing disability in spatial learning (CRF) |
| Investigator(s): | Chan YS |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Seed Funding for Strategic Interdisciplinary Research Scheme |
| Start Date: | 04/2018 |
| List of Research Outputs |
| Tsui Y.P., Shea G.K.H., Chan Y.S. and Shum D.K.Y., Derivation of Fate-Committed Schwann Cells from Bone Marrow Stromal Cells of Adult Rats., In: Paula V. Monje, Haesun A. Kim, Schwann Cells: Methods and Protocols. Springer, 2018, MIMB, volume 1739: 137-148. |
| Researcher : Chen Z |
| Project Title: | A novel model for the study of lung pathogenesis of SARS |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | National Institutes of Health, US Department of Health and Human Services - General Award |
| Start Date: | 08/2007 |
| Project Title: | Understanding the Ongoing HIV Epidemic in Yunnan China |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | China AIDS Initiative - General Award |
| Start Date: | 05/2008 |
| Project Title: | Preventing HIV-1 infection using a novel vaccine immunogen |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Global Health Grants |
| Start Date: | 10/2008 |
| Project Title: | Establishment of a rapid, high-throughput, cost-effective HIV-1 drug resistance testing system |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 05/2011 |
| Project Title: | A Novel Vaccine for Mesothelioma Immunotherapy and Prevention; |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Pneumoconiosis Compensation Fund Board - General Award |
| Start Date: | 07/2011 |
| Project Title: | AIDS Vaccine 2011 A Novel Vaccine Design for Inducing Robust HIV-1 Specific Immunity |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2011 |
| Project Title: | Blocking HIV infection by gene-encoding neutralizing antibodies |
| Investigator(s): | Chen Z, Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2012 |
| Project Title: | AIDS Vaccine 2012; Mucosal Prime with a Replicating Vaccinia-based Vaccine Promotes Mucosal Immunity against SIV. |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2012 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Guangdong-Hong Kong Technology Cooperation Funding Scheme |
| Start Date: | 07/2013 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 12/2013 |
| Project Title: | Mechanism of potentiating HIV antigen-specific CD8+ T cells |
| Investigator(s): | Chen Z, Liu L, Yam WC, Cheung KLA, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2014 |
| Project Title: | A New Therapeutic Vaccine for HIV/AIDS |
| Investigator(s): | Chen Z, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 3) |
| Start Date: | 12/2014 |
| Project Title: | Role of a newly identified PD-1 isoform in modulating immune responses |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Completion Date: | 12/2017 |
| Project Title: | A New Therapeutic Vaccine for HIV/AIDS |
| Investigator(s): | Chen Z, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2015 |
| Project Title: | A novel PDI DNA-based vaccination strategy to mimic Gag-specific responses found in HIV Elite controllers |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | ANR / RGC Joint Research Scheme |
| Start Date: | 04/2015 |
| Project Title: | Role of Δ42PD1 in HIV Infection |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Induction of Mesothelioma-Specific CD8+ T Cell Response for Immunotherapy and Prevention |
| Investigator(s): | Chen Z, Man K |
| Department: | Microbiology |
| Source(s) of Funding: | Pneumoconiosis Compensation Fund Board - General Award |
| Start Date: | 09/2015 |
| Project Title: | Role of PD1-Based Vaccine-Elicited CD8+ T Lymphocytes in Modulating MDSC-associated Immunosuppression |
| Investigator(s): | Chen Z, Cheung KLA, Tan Z |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Project Title: | A Therapeutic Bi-Specific Neutralizing Antibody for HIV/AIDS |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Fund for Translational and Applied Research |
| Start Date: | 01/2017 |
| Project Title: | Study on AIDS Vaccine and Immunotherapy |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | 醫療衛生三名工程 |
| Start Date: | 01/2017 |
| Project Title: | Potency of latency reversing drug combinations for purging HIV-1 reservoir of TGFβ1-induced resting CD4 T cells |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2017 |
| Completion Date: | 03/2018 |
| Project Title: | Structure-based vaccine design against HIV-1 |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Foundation for the National Institutes of Health (FNIH) |
| Start Date: | 04/2017 |
| Project Title: | Induction of Mesothelioma-Specific CD8+ T Cell Response for Immunotherapy and Prevention |
| Investigator(s): | Chen Z, Man K |
| Department: | Microbiology |
| Source(s) of Funding: | Pneumoconiosis Compensation Fund Board - General Award |
| Start Date: | 05/2017 |
| Project Title: | Novel human neutralizing antibodies against HIV/AIDS |
| Investigator(s): | Chen Z, Yuen KY |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 08/2017 |
| Project Title: | 2017 CALDAR Summer Institute & International Global Health Conference; A Useful Humanized Mouse Model for HIV-1 Cure Research |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 08/2017 |
| Completion Date: | 08/2017 |
| Project Title: | A Novel Therapeutic AAV-vectored Bi-Specific Neutralizing Antibody against HIV/AIDS |
| Investigator(s): | Chen Z, Tan Z |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 3) |
| Start Date: | 01/2018 |
| Project Title: | A Novel PD1-based Vaccine for HIV/AIDS Immunotherapy |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Matching Grant for Joint Research |
| Start Date: | 03/2018 |
| Project Title: | The role of a novel PD-1 isoform in regulating tumour-specific CD8+ T cell functions in hepatocellular carcinoma patients |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2018 |
| Project Title: | Potentiating host immunity for HIV-1 functional cure (TRS) |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Funding for Strategic Interdisciplinary Research Scheme |
| Start Date: | 04/2018 |
| Project Title: | Humanized Mouse Models for Infection and Cancer Research |
| Investigator(s): | Chen Z, Man K, Tsao GSW |
| Department: | Microbiology |
| Source(s) of Funding: | Platform Technology Funding |
| Start Date: | 06/2018 |
| Researcher : Cheung KS |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Researcher : Fan KL |
| Project Title: | Compression-only CPR Training Program for Secondary School Students |
| Investigator(s): | Fan KL, Leung LP |
| Department: | The University of Hong Kong |
| Source(s) of Funding: | Quality Education Fund |
| Start Date: | 10/2016 |
| List of Research Outputs |
| Ho C., Chan T., Leung N.A., Leung C.M.R., Fan K.L. and Leung L.P., Are the Filipino domestic helpers caring the home-dwelling elders in Hong Kong competent to provide first aid in a medical emergency?, Hong Kong Journal of Emergency Medicine. 2018, 0(0): 1024907918779529. |
| Leung L.P., Fan M. and Fan K.L., Distribution, accessibility and coverage of auttomated external defibrillators in public locations in Hong Kong, Scientific Symposium in Emergency Medicine. Hong Kong, 2017. |
| Leung S.C., Leung C.M.R., Fan K.L. and Leung L.P., Elderly Out-of-Hospital Cardiac Arrest – A Population-wide Analysis of Prehospital Registry Data, Scientific Symposium on Emergency Medicine 2017 – Geriatric Emergency Care: Embracing the Challenges, Hong Kong. 2017. |
| Leung S.C., Leung C.M.R. and Fan K.L., Elderly out-of-hospital cardiac arrest - a population wide analysis of prehospital registry data, Scientific Symposium in Emergency Medicine. 2017. |
| Researcher : Fan M |
| List of Research Outputs |
| Leung L.P., Fan M. and Fan K.L., Distribution, accessibility and coverage of auttomated external defibrillators in public locations in Hong Kong, Scientific Symposium in Emergency Medicine. Hong Kong, 2017. |
| Researcher : He M |
| Project Title: | Regulation of ion channels by angiotensin II in human cardiac fibroblasts |
| Investigator(s): | He M, Li GR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2009 |
| Researcher : Hui EC |
| Project Title: | Promotion of the reflection, dialogue and teaching of ethical issues related to the development and uses of biotechnologies among students and faculty members of health-related sciences at the University of Hong Kong |
| Investigator(s): | Hui EC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Teaching Development Grants |
| Start Date: | 03/2005 |
| Researcher : Lai WWK |
| Project Title: | Open label, prospective, double arm, randomized, pilot study to evaluate the safety and efficacy of the same day administration of PDT with verteporfin and an intravitreal injection of ranibizumab vs. ranibizumab monotherapy for the treatment of subfoveal CNV secondary to neovascular age related macular degeneration in the Asian population |
| Investigator(s): | Lai WKW, Li KKW, Wong DSH, McGhee S, Lam CLK, Chan WSC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Pharmaceutical Industry - General Award |
| Start Date: | 07/2008 |
| Project Title: | Production of Iris Pigment Epithelial Cells for transplantation to treat Age-Related Macular Degeneration |
| Investigator(s): | Lai WKW, Lo ACY, Fletcher C, Wong DSH |
| Department: | Ophthalmology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2009 |
| Researcher : Lam PK |
| List of Research Outputs |
| Chia K.L., Lam P.K., Lam C.K. and Tsui S.H., Acupuncture in the emergency department: a systematic review of randomised controlled trials, Acupuncture in Medicine. 2018, 36: 183-192. |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Lam P.K., Choi Y.P., Yip W.L., Wan C.K. and Tsui S.H., Dragon’s Tongue (Sauropus spatulifolius)-induced liver injury – a report of two cases, North American Congress of Clinical Toxicology (NACCT) 2017. 55: 689-868. |
| Lam P.K., Balsari S., Hung K.K.C., Hsiao K.H., Leung L.P. and Leaning J., How Do Doctors and Nurses in Emergency Departments in Hong Kong View Their Disaster Preparedness? A Cross-Sectional Territory-Wide Online Survey, Disaster Medicine and Public Health Preparedness. 2017, 1-8. |
| Lam P.K., Tang M.H.Y., Leung S.C., Chong Y.K., Tsui M.S.H. and Mak T.W.L., Supraventricular tachycardia and acute confusion following ingestion of e-cigarette fluid containing AB-FUBINACA and ADB-FUBINACA: a case report with quantitative analysis of serum drug concentrations, Clinical Toxicology. 2017, 55: 662-667. |
| Lam P.K., Balsari S., Hung K.C., Hsiao K.H. and Leaning J., Urban disaster preparedness of Hong Kong residents: A territory-wide survey, International Journal of Disaster Risk Reduction. 2017, 23: 62-69. |
| Leung J.K. and Lam P.K., Hyperbaric oxygen therapy: its use in medical emergencies and its development in Hong Kong, Hong Kong Medical Journal. 2018, 24. |
| Newnham E.A., Balsari S., Lam P.K., Kashyap S., Pham P., Chan E.Y.Y., Patrick K. and Leaning J., Self-efficacy and barriers to disaster evacuation in Hong Kong, International Journal of Public Health . 2017. |
| Wong K.W. and Lam P.K., A patient with diabetic ketoacidosis and Klebsiella pneumoniae metastatic infection, Visual Journal of Emergency Medicine. 2018, 10: 95-7. |
| Researcher : Lam SK |
| Project Title: | Biotech Company in the Faculty of Medicine, The University of Hong Kong |
| Investigator(s): | Lam SK |
| Department: | Medicine |
| Source(s) of Funding: | The University of Hong Kong Foundation Seed Grant |
| Start Date: | 07/2003 |
| Project Title: | Treatment of gastrointestinal cancer by targeting survivin using adeno-associated virus gene delivery system |
| Investigator(s): | Lam SK, Wong CYB, Lin MC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2004 |
| Researcher : Lau FL |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Researcher : Lau WCS |
| Project Title: | Prospective study of the clinical pattern of systemic lupus erythematosus in Hong Kong |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1993 |
| Project Title: | Effects of sex hormones on lymphocyte function in systemic lupus erythematosus |
| Investigator(s): | Lau WCS, Mok MYT |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2002 |
| Project Title: | A study to evaluate the immunopathology of Severe Acute Respiratory Syndrome |
| Investigator(s): | Lau WCS, Chan YTE, Cheung BMY |
| Department: | Medicine |
| Source(s) of Funding: | VCO SARS Research Fund |
| Start Date: | 07/2003 |
| Project Title: | Evaluation of the effects of sex hormones on neutrophils and macrophage apoptosis and macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Project Title: | Dendritic cell function and their effects on B cell activation in systemic lupus erythematosus |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2005 |
| Project Title: | Interactions between plasmacytoid dendritic cells and T regulatory / interleukin-17 producing T-helper cells in systemic lupus erythematosus |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2012 |
| Project Title: | The role of plasmacytoid dendritic cells in systemic lupus erythematosus |
| Investigator(s): | Lau WCS, Chan VSF |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2013 |
| Project Title: | Advances in Immunology in Health and Disease |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Croucher Summer Courses |
| Start Date: | 07/2014 |
| Project Title: | Validation of a new definition of lupus low disease activity state (LLDAS): Clinical and management implications |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Centre for Research into Circulating Fetal Nucleic Acids |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Theme-based Research Scheme |
| Start Date: | 01/2016 |
| List of Research Outputs |
| See C.Y.H., Ng E., Fong D.Y.T., Lau W.C.S. and Lam T.P., Medical Student Peer-created E-learning Resources in Social Media: A Mixed-Methods Study. , Asian Medical Education Association (AMEA) Conference, 13th December 2017, Hong Kong.. 2017. |
| Researcher : Lee AM |
| Project Title: | Prevalence and risk factors for paternal depression and anxiety in the antenatal period |
| Investigator(s): | Lee AM, Chung KF, Fong DYT, Law ACK, Leung KY |
| Department: | Psychiatry |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2009 |
| List of Research Outputs |
| Lee C.F., Ho J.W.C., Fong D.Y.T., Macfarlane D.J., Cerin E., Lee A.M., Leung S., Chan W.Y.Y., Leung I.P.F., Lam S.H.S., Chu N., Taylor A.J. and Cheng K.K., Dietary and physical activity interventions for colorectal cancer survivors: a randomized controlled trial, Scientific Reports. 2018, 8: 5731. |
| Researcher : Leung AYH |
| Project Title: | Detection of WU and KI polyomaviruses from patients with acute respiratory tract infections in Hong Kong |
| Investigator(s): | Leung AYH, Kwong YL |
| Department: | Medicine |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 01/2009 |
| Project Title: | Study of Microglia and Myeloid Leukemia in Zebrafish |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 05/2013 |
| Project Title: | Development of Cell Manipulation Tools for Probing Functional Mechanism of Hematopoietic Cells: Robotics, Optical tweezers, and Hematopoiesis |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2014 |
| Project Title: | Provision of free next generation sequencing (NGS) service of prognostic and therapeutic values for patients with acute myeloid leukemia in Hong Kong |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 03/2016 |
| Project Title: | Establish a zebrafish model to study the molecular and clonal heterogeneity and develop personalized treatment in FLT3-ITD+ AML |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 09/2016 |
| Project Title: | Provision of free decitabine for young patients with acute myeloid leukemia (AML) carrying DNMT3A mutation |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 02/2017 |
| Project Title: | A Comprehensive and Multidisciplinary Approach Targeting Acute Myeloid Leukaemia in Hong Kong (TRS) |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding for Strategic Interdisciplinary Research Scheme |
| Start Date: | 06/2017 |
| Project Title: | Targeting DNA damage and repair mechanism in FLT3-ITD acute myeloid leukaemia (AML) - a mechanistic and therapeutic study |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 07/2017 |
| Project Title: | Follistatin as a novel target and biomarker for acute myeloid leukaemia (AML) carrying internal tandem duplication (ITD) of Fms-Like Tyrosine kinase 3 (FLT3). |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2018 |
| Project Title: | Develop a high throughput platform for personalized treatment of acute myeloid leukaemia |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Croucher Senior Medical Research Fellowships |
| Start Date: | 01/2018 |
| Project Title: | Provision of Free Azacitidine as Maintenance Therapy for Haematopoietic Stem Cell Transplant Recipients at High Risk of Relapse from Acute Myeloid Leukaemia |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 06/2018 |
| List of Research Outputs |
| Lam S.Y., He B.A. and Leung A.Y.H., Treatment of acute myeloid leukemia in the next decade - Towards real-time functional testing and personalized medicine, Blood Rev. 2017. |
| Ma A.C.H., Shi X., He B.A., Guo Y. and Leung A.Y.H., A Zebrafish Model for Evaluating the Function of Human Leukemic Gene IDH1 and Its Mutation, Methods Mol Biol. 2017, 1633: 193-218. |
| Usman W.M., Pham T.C., Kwok Y.Y., Vu L.T., Ma V., Peng B., Chan Y.S., Wei L., Chin S.M., Azad A., He B.A., Leung A.Y.H., Yang M., Shyh-Chang N., Cho W.C., Shi J. and Le M.T.N., Efficient RNA drug delivery using red blood cell extracellular vesicles, Nat Commun. 2018, 9(1): 2359. |
| Researcher : Leung CMR |
| List of Research Outputs |
| Leung S.C., Leung C.M.R., Fan K.L. and Leung L.P., Elderly Out-of-Hospital Cardiac Arrest – A Population-wide Analysis of Prehospital Registry Data, Scientific Symposium on Emergency Medicine 2017 – Geriatric Emergency Care: Embracing the Challenges, Hong Kong. 2017. |
| Researcher : Leung GM |
| Project Title: | Evidence-based practice (EBP) learning in the undergraduate medical curriculum - where is the evidence? |
| Investigator(s): | Leung GM, Fielding R, Ho LM, Johnston JM, Lam TH |
| Department: | Community Medicine |
| Source(s) of Funding: | Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants |
| Start Date: | 01/2003 |
| Project Title: | A controlled trial of masks and hand hygiene for reducing influenza transmission |
| Investigator(s): | Leung GM, Cowling BJ, Peiris JSM, Ho LM |
| Department: | Community Medicine |
| Source(s) of Funding: | National Center for Infectious Diseases (NCID) |
| Start Date: | 09/2006 |
| Project Title: | Preventing breast cancer in Hong Kong Chinese women through personalised risk stratification and characterisation: an epidemiologic modelling study and the development of a biorepository of cases and controls |
| Investigator(s): | Leung GM, Kwong A, Wong OL, Lam WWT, Khoo US |
| Department: | School of Public Health |
| Source(s) of Funding: | Commissioned Study on Risk of Breast Cancer in Hong Kong |
| Start Date: | 10/2015 |
| Project Title: | Evaluating the health and health care impact of Hong Kong’s pilot colorectal cancer screening programme |
| Investigator(s): | Leung GM, Law WL, Leung WK |
| Department: | School of Public Health |
| Source(s) of Funding: | Commissioned Study on Evaluation of Government's Colorectal Cancer Screening Pilot Programme |
| Start Date: | 12/2015 |
| List of Research Outputs |
| CHENG T.S., Kwok M.K., Leung G.M. and Schooling C.M., The associations of breast feeding with infant growth and body mass index to 16 years: ‘Children of 1997’, Paediatric and Perinatal Epidemiology. 2018, 32: 200-209. |
| Ip D.K.M., Lau E.H.Y., So H.C., Xiao J., Lam C.K., Fang J., Tam Y.H., Leung G.M. and Cowling B.J., A Smart Card-Based Electronic School Absenteeism System for Influenza-Like Illness Surveillance in Hong Kong: Design, Implementation, and Feasibility Assessment., JMIR Public Health and Surveillance. 2017, 3(4): e67. |
| Ip D.K.M., So H.C., Xiao J., Fang J., Leung G.M., Kwok H.K.H. and Cowling B.J., Temporal pattern of acute respiratory infection related productivity loss impact among health care workers over the course of seasonal influenza epidemics in Hong Kong, The 21st International Epidemiological Association World Congress of Epidemiology. 2017. |
| Jiang H., Wu P., Uyeki T.M., He J., Deng Z., Xu W., Lv Q., Zhang J., Wu Y., Tsang K.L., Kang M., Zheng J., Wang L., YANG B., Qin Y., Feng L., Fang J., Gao G.F., Leung G.M., Yu H. and Cowling B.J., Preliminary epidemiologic assessment of human infections with highly pathogenic avian influenza A(H5N6) virus, China, Clinical Infectious Diseases. 2017, 65: 383-388. |
| Kwok M.K., Leung G.M., Chung T.W.H., Lee K.K.Y. and Schooling C.M., Divergent secular trends in blood pressure and body mass index in children and adolescents in Hong Kong, Scientific Reports. 2017, 7: 4763. |
| Kwok M.K., Schooling C.M., Subramanian S.V., Leung G.M. and Kawachi I., Opposite associations of household income with adolescent body mass index according to migrant status: Hong Kong’s “Children of 1997” birth cohort, International Journal of Obesity. 2018, 42: 1221-1229. |
| LIU J., Au Yeung S.L.R., Kwok M.K., Leung Y.Y.J., Lin S.C., Hui L.L., Leung G.M. and Schooling C.M., Birth weight, gestational age and late adolescent liver function using twin status as instrumental variable in a Hong Kong Chinese birth cohort: “Children of 1997”, Preventive Medicine. 2018, 111: 190-197. |
| Leung G.M., 大醫精誠 – 香港醫學發展一百三十年, 香港三聯書店, 2018. |
| Quan J., Li K.L., Pang H.M.H., Choi C.H., Siu S.C., Tang S.Y., Wat N.M., Woo J., Johnston J.M. and Leung G.M., Diabetes incidence and prevalence in Hong Kong, China during 2006-2014, Diabetic Medicine. 2017, 34(7): 902-8. |
| Wei D.M., Au Yeung S.L.R., He J.R., Xiao W.Q., Lu J.H., Tu S., Chen N.N., Lam K.B.H., Cheng K.K., Leung G.M., Xia H.M., Schooling C.M. and Qiu X., The role of social support in family socio-economic disparities in depressive symptoms during early pregnancy: Evidence from a Chinese birth cohort, Journal of Affective Disorders. 2018, 238: 418-423. |
| YANG Q., Lin S.C., Au Yeung S.L.R., Kwok M.K., Xu L., Leung G.M. and Schooling C.M., Genetically predicted milk consumption and bone health, ischemic heart disease and type 2 diabetes: a Mendelian randomization study, European Journal of Clinical Nutrition. 2017, 71: 1008-1012. |
| Researcher : Leung LP |
| Project Title: | Disaster Response and Rehabilitation in the Rural Setting: A Massive Open Online Course |
| Investigator(s): | Leung LP |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | China Medical Board |
| Start Date: | 01/2016 |
| Project Title: | Identifying hidden psychotropic substance abusers among patient attending the Accident & Emergency departments in Hong Kong |
| Investigator(s): | Leung LP, Fan KL |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Beat Drugs Fund Association |
| Start Date: | 08/2016 |
| List of Research Outputs |
| Fan K.L., Lui C.T. and Leung L.P., Public access defibrillation in Hong Kong in 2017, Hong Kong Medical Journal. 2017. |
| Ho C., Chan T., Leung N.A., Leung C.M.R., Fan K.L. and Leung L.P., Are the Filipino domestic helpers caring the home-dwelling elders in Hong Kong competent to provide first aid in a medical emergency?, Hong Kong Journal of Emergency Medicine. 2018, 0(0): 1024907918779529. |
| Lam P.K., Balsari S., Hung K.K.C., Hsiao K.H., Leung L.P. and Leaning J., How Do Doctors and Nurses in Emergency Departments in Hong Kong View Their Disaster Preparedness? A Cross-Sectional Territory-Wide Online Survey, Disaster Medicine and Public Health Preparedness. 2017, 1-8. |
| Leung L.P., Fan M. and Fan K.L., Distribution, accessibility and coverage of auttomated external defibrillators in public locations in Hong Kong, Scientific Symposium in Emergency Medicine. Hong Kong, 2017. |
| Leung L.P., Editor-in-chief of Hong Kong Journal of Emergency Medicine, 2017. |
| Leung L.P., How does technology inform health care system development, and the advancement of medical and biological sciences in health care treatment?, Symposium on STEM education, Academy for the talented, HKU. 2017. |
| Leung S.C., Leung C.M.R., Fan K.L. and Leung L.P., Elderly Out-of-Hospital Cardiac Arrest – A Population-wide Analysis of Prehospital Registry Data, Scientific Symposium on Emergency Medicine 2017 – Geriatric Emergency Care: Embracing the Challenges, Hong Kong. 2017. |
| Yang W.X., Fan K.L. and Leung L.P., A cluster of patients with rhabdomyolysis after eating crayfish, CJEM. 2017. |
| Researcher : Leung SC |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Leung S.C., 2017 Distinguished Young Fellow, Hong Kong Academy of Medicine. 2017. |
| Leung S.C., Editor, Hong Kong Journal of Emergency Medicine. 香港急症醫學期刊, United States, SAGE Publishing, 2017. |
| Leung S.C., Leung C.M.R., Fan K.L. and Leung L.P., Elderly Out-of-Hospital Cardiac Arrest – A Population-wide Analysis of Prehospital Registry Data, Scientific Symposium on Emergency Medicine 2017 – Geriatric Emergency Care: Embracing the Challenges, Hong Kong. 2017. |
| Researcher : Li CB |
| Project Title: | The role of c-Myc in anti-mycobaterial responses: from bacterial killing to T cell activation |
| Investigator(s): | Li CB, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | A role for interleukin-17A in influenza virus induced immune responses and viral replication |
| Investigator(s): | Li CB |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| List of Research Outputs |
| Li C.B., BMC Immunology, Section Editor, BMC Immunology. 2017. |
| Yang L.H., Or C.T., Li C.B. and Law H.Y., Novel therapeutic methods for treating inflammation and modulating immune responses, PI: Allan SY Lau. Co-I: Cindy LH Yang and Terry CT Or, James CB Li and Anna HY Law. Owner: HKU Versitech Limited and Bagi Research Limited. European Patent No: 2866638., 2017. |
| Researcher : Li G |
| Project Title: | The 10th International Conference on Alzheimer's Disease and Related Disorders High Field MRI Study of the Beta Amyloid and Plaque Desposits in the Brain of APP/PS1 Mice CoQ10 Delays the Brain Atrophy in Transgenic Aged Mice: in Vivo Volume MRI Study |
| Investigator(s): | Li G |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2006 |
| Project Title: | Effect of imbalance of kinases and protein phosphatases on deposit of B amyloid and Tau Pathology in double transgenic APP/PS1 Mice |
| Investigator(s): | Li G, Yang X, Yang ES |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Germany/Hong Kong Joint Research Scheme |
| Start Date: | 01/2007 |
| Researcher : Li Q |
| List of Research Outputs |
| Chan L.K., Ganotice F.J.A., Wong F.K.Y., Lau W.C.S., Bridges S.M., Chan C.H.Y., Chan N.K., Chan W.L.P., Chen H., Chen J.Y., Chu K.P.J., Ho C.C., Ho J.M.C., Lam T.P., Lam S.F., Li Q., Shen J., Tanner J.A., Tso W.Y.W., Wong A.K.C., Wong G.T.C., Wong J.Y.H., Wong N.S., Worsley A.J., Yu L.K. and Yum T.P., Implementation of an interprofessional team-based learning program involving seven undergraduate health and social care programs from two universities, and students’ evaluation of their readiness for interprofessional learning, BMC Medical Education. 2017, 17. |
| Chan L.K., Ganotice F.J.A. and Li Q., Team-based learning implemented on paper vs. electronic platform in an interprofessional programme in Hong Kong, Ninth Asia Medical Education Association Symposium cum Frontiers in Medical and Health Sciences Education . 2017. |
| Researcher : Liu L |
| Project Title: | Early HIV-1 diagnosis using in-house real-time PCR amplification on dried blood spots for men who have sex with men in Hong Kong |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 09/2009 |
| Project Title: | Molecular mechanisms of Nef mediated regulation of PD-1 expression during HIV/SIV infection |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Completion Date: | 02/2018 |
| Project Title: | Defining the role of monocyte-derived dendritic cells in potentiating durable and protective T-cell immunity by a newly identified PD-1 isoform |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Completion Date: | 12/2017 |
| Project Title: | Mechanisms of viral evasion of vaccine induced T cell immune response |
| Investigator(s): | Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Completion Date: | 05/2018 |
| Project Title: | Therapeutic potential of regulatory T cells in limiting HIV reservoir in the brain without triggering detrimental neuroinflammation |
| Investigator(s): | Liu L, Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2017 |
| Project Title: | Role of Δ42PD-1 in B-cell dysfunction during HIV infection |
| Investigator(s): | Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | IMMUNOLOGY 2018; Aberrant innate immune activation facilitates EcoHIV evasion from vaccine-induced protection |
| Investigator(s): | Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2018 |
| Completion Date: | 05/2018 |
| Researcher : Lok S |
| Project Title: | Generation of ferret (Mustela putorius furo) genomic resources for respiratory infectious disease research: Transcriptomics and comprehensive characterization of cDNAs in a model of influenza infection |
| Investigator(s): | Lok S, Tong AHY, Lee MY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 04/2011 |
| Researcher : Mok KL |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Researcher : Ng F |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Researcher : Rong J |
| Project Title: | The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy |
| Investigator(s): | Rong J |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2006 |
| Project Title: | Novel caffeic acid derivatives promote the phenotypic and functional switch of macrophages toward resolution of inflammation and cardiac regeneration after myocardial infarction |
| Investigator(s): | Rong J, Li XC |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2015 |
| Project Title: | ω-Alkynyl arachidonic acid induces anti-inflammatory M2 polarization of macrophages in acute myocardial infarction via regulating the cross-talk between PKM2, iNOS and HIF-1α |
| Investigator(s): | Rong J, Feng Y, Xia Z, Li XC |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2017 |
| Project Title: | Chinese medicine celastrol ameliorates inflammation and metabolic dysfunction in adipose tissues via covalent modification of ER chaperone GRP78/BiP |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2017 |
| Completion Date: | 03/2018 |
| Project Title: | Plant-derived celastrol ameliorates metabolic dysfunctions, oxidative stress and inflammation in diet-induced obesity via disrupting the cross-talk between PKM2, HIF-1α and IL-1β |
| Investigator(s): | Rong J, Xia Z, Li XC, Wang Y |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2018 |
| Project Title: | Chinese medicine celastrol inhibits atherosclerotic foam cell formation via reducing lipid accumulation and ameliorating ER stress in diet-induced obese mice |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2018 |
| Researcher : Sham PC |
| Project Title: | Replication study of susceptibility genes for colorectal cancer |
| Investigator(s): | Sham PC, Ho JWC, Cheng KK |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2007 |
| Project Title: | Partner State Key Laboratory of Brain and Cognitive Sciences |
| Investigator(s): | Sham PC, So KF, Tan L |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Matching Fund for State Key Laboratory (SKL) |
| Start Date: | 10/2008 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Sham PC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | Genomics |
| Investigator(s): | Sham PC, Chin FYL, Leung FCC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2013 |
| Project Title: | Cross Cultural Differences in Biased Cognition |
| Investigator(s): | Sham PC, Chen EYH, Toulopoulou T |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | ESRC/RGC Joint Research Scheme |
| Start Date: | 09/2013 |
| Completion Date: | 08/2017 |
| Project Title: | A novel computational framework to identify transcription factor-DNA interaction for cancer genomics |
| Investigator(s): | Sham PC, Yao KM, Wong MP, Wang JJ |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 08/2014 |
| Completion Date: | 07/2017 |
| Project Title: | Schizophrenia-related de novo and compound heterozygous mutations |
| Investigator(s): | Sham PC, Chen EYH, Chang WC, Chan KW, Lee HME, Cherny SS, Li M |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2015 |
| Project Title: | Method and software tool for estimating and dissecting the heritability of complex diseases |
| Investigator(s): | Sham PC, Cherny SS, Li M |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2015 |
| Project Title: | Establishment of Third Generation Sequencing Core Facility |
| Investigator(s): | Sham PC, Leung SY, Peiris JSM, Poon LML, Woo PCY, Yuen KY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Major Equipment Project |
| Start Date: | 04/2017 |
| Project Title: | Genetic Variation and Genomic Architecture in Development, Health and Disease |
| Investigator(s): | Sham PC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Croucher Advanced Study Institute |
| Start Date: | 12/2017 |
| Project Title: | Integrating functional annotation and statistical information in novel set-based rare-variants association tests for complex diseases |
| Investigator(s): | Sham PC, Cherny SS, Li M, Tang SM |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2018 |
| Project Title: | New-generation high-performance computer cluster for studying the role of complex genomic variations in development and disease |
| Investigator(s): | Sham PC, Cheah KSE, Garcia-Barcelo MM, Ng IOL, Ngan ESW, Yang W |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Small Equipment Grant |
| Start Date: | 04/2018 |
| Researcher : Sharma R |
| List of Research Outputs |
| Liu A.J., RAO Y., Cheung M.P.L., Hui M.N., Wu M.H., Chan L.K., Ng I.O.L., Niu B., Cheah K.S.E., Sharma R., Hodgson L. and Cheung M.C.H., Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration, In: J Ann Le Good, Nature Communications. 2017, 8: 1185. |
| RAO Y., Cheung M.P.L., Liu A.J., Sharma R. and Cheung M.C.H., A dual role for DLC1 in regulating avian cranial neural crest cell fate commitment and delamination, The Hong Kong Inter-University Postgraduate Symposium in Biomedical Sciences. 2018. |
| Sharma R., Proteomic profiling of plasma proteins associated with spontaneous hepatitis B surface antigen seroclearance in chronic hepatitis B, Journal of Hepatology . 2017, 66: S484-S485. |
| Researcher : Tsui MSH |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Researcher : Wai KCA |
| List of Research Outputs |
| Wai K.C.A., Protection of rescuers in emergency care: where does Hong Kong stand?, Hong Kong Medical Journal. 2017, 656-657. |
| Researcher : Wong DSH |
| Project Title: | The Royal College of Ophthalmologists Annual Congress 2009 Can Lutein Protect the Outer Retina? |
| Investigator(s): | Wong DSH |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2009 |
| Researcher : Wong ICK |
| Project Title: | Feasibility study of the effects of clonidine and melatonin treatment on sleep architecture of children with ADHD. |
| Investigator(s): | Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Translational and Applied Research |
| Start Date: | 04/2015 |
| List of Research Outputs |
| Man K.C.K., Chan E.W., Ip P., Coghill D., Simonoff E., Chan P.K.L., Lau W.C.Y., Schuemie M.J., Sturkenboom M.C.J.M. and Wong I.C.K., Prenatal antidepressant exposure and the risk of attention-deficit hyperactivity disorder in children: A systematic review and meta-analysis, Neuroscience & Biobehavioral Reviews. 2018, 86: 1-11. |
| Researcher : Wong KW |
| List of Research Outputs |
| Wong K.W. and Lam P.K., A patient with diabetic ketoacidosis and Klebsiella pneumoniae metastatic infection, Visual Journal of Emergency Medicine. 2018, 10: 95-7. |
| Researcher : Wong TW |
| List of Research Outputs |
| Chung C.H., Chung A.H.Y., Ng F., Lau F.L., Tsui M.S.H., Wong T.W., Mok K.L., Cheung K.S., Chan Y.C., Leung S.C., Lam P.K., Wan C.K., Liu S.H., Chan T.S., Chan H.Y., Ng M.H., Kwok W.W.H., Lam K.C., Wong W.T. and Wu K.W.C., 急症的B：爭一口氣, 生命邊緣的守護者 - 急症醫 護最前線, Hong Kong, 商務印書館, 2018, 92-100. |
| Researcher : Wu HY |
| Project Title: | Glasgow/HKU Early Career Mobility Funds 2017-18 |
| Investigator(s): | Wu YH |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Glasgow/HKU Early Career Mobility Fund |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Researcher : Wu YH |
| Project Title: | Glasgow/HKU Early Career Mobility Funds 2017-18 |
| Investigator(s): | Wu YH |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Glasgow/HKU Early Career Mobility Fund |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Chen J.Y., Wu Y.H., Wright A., Kwan J.S.K., Leung G.K.K., Tsang J.P.Y. and Lau W.C.S., Moral distress in medical students: what ethical dilemmas did Hong Kong medical students identify in their clinical clerkships?, Chinese University Medical Education Conference (CUMEC) 2018. |
| Chen J.Y. and Wu Y.H., “White coat and purple coat”: the experience of integrating medical humanities in the core medical school curriculum. , Creating Space VIII/ Canadian Conference on Medical Education, Halifax, Canada. . 2018. |
| Wu Y.H., Andrew Schonebaum, Novel Medicine: Healing, Literature, and Popular Knowledge in Early Modern China (Seattle, WA: University of Washington Press, 2016), pp.?296, $50,00, hardcover, ISBN:?9780295995182., Medical History. 2017, 61: 468-470. |
| Wu Y.H. and Onaga L., Articulating Genba: Particularities of Exposure and Its Study in Asia, In: Tani Barlow, Positions: Asia Critique. Duke University Press, 2018, 26(2): 197-212. |
| Wu Y.H., From Colonial Subjects to Life Presents: The Transformation of Chinese Bodies, Transplant Ethics: Looking Forward. 2018. |
| Wu Y.H., Invisible Victims in the Prosperous Port City: Hazardous Exposures and the Constraint of Science in Hong Kong, Medical Humanities, Social Science and the Environment Conference, Harvard University. 2017. |
| Wu Y.H., Lomax’s asylum affair on Dr Fat-im Tseung’s bookshelf, Hong Kong Medical Journal. Hong Kong, Hong Kong Academy of Medicine, 2018, 24(3): 323-324. |
| Wu Y.H., Six domains to develop critical medical humanities, The Clinical Teacher. 2017. |
| Wu Y.H., Temperature charts from Bombay, Hong Kong Medical Journal. Hong Kong, Hong Kong Academy of Medicine, 2017, 23(5): 545–7. |
| Wu Y.H., Lin R.T., Wang J.D. and Cheng Y., Transnational Dynamics Amid Poor Regulations: Taiwan’s Asbestos Ban Actions and Experiences, International Journal of Environmental Research and Public Health. 2017, 14(10). |
| Researcher : Yang LH |
| List of Research Outputs |
| Yang L.H. and Chik S.C.C., Compounds and Uses Thereof for Treating Inflammation and Modulating Immune Responses., Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang and Stanley C Chik. Taiwanese Patent No: I600426, , 2017. |
| Researcher : Yau JMH |
| Project Title: | Angiopoietin-like proteins 3 and 4 as novel inhibitors of lipoprotein lipase: functional and structural studies |
| Investigator(s): | Yau JMH, Xu A, Lam KSL |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2006 |
| Researcher : Zhi H |
| List of Research Outputs |
| Zhi H., Stroke & Vascular Neurology (SVN) Most Impact Paper Award, 2017年度国内最具影响力文章奖, 2018. |