DEPT OF OBSTETRICS & GYNAECOLOGY



Researcher : CHEN CH

List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
Lee C.Y.L., PENG Q., Fong S.W., CHEN C.H., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways, PLoS One. 2012, 7(9): e45633.


Researcher : CHEONG WYA

List of Research Outputs

CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., The estrogen-regulated Let-7a plays a pivotal role during blastocyst activation via its effect on Vav3, The 7th International Huaxia Congress of Endocrinology, Hong Kong. 2012.


Researcher : Cai C

List of Research Outputs

Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFkB activity is associated with the aggressiveness of ovarian cancers, 17th Research Postgraduate Symposium . 2012.
Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFkB activity is associated with the aggressiveness of ovarian cancers, 19th Hong Kong International Cancer Congress . 2012.
Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFB activity is associated with the aggressiveness of ovarian cancers, European Association of Cancer Research (EACR) 2012 Congress, Barcelona 7 -10 July 2012.
Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Chan D.W., Cai C., Yung M.H. and Ngan H.Y.S., The AMPK/TAK1 signaling axis is indispensable for controlling ovarian cancer cell metabolism and omental metastasis, COLD SPRING HARBOR ASIA CONFERENCES: Metabolism, Obesity and Obesity-associated Diseases. Suzhou Dushu Lake Conference Center May 20-24, 2013. Suzhou, Jiangsu Province, China.. Suzhou, Jiangsu Province, China., 2013.
Kwan H.T., Chan D.W., Cai C., Mak S.L., Yung M.H., Leung T.H.Y., Wong G.W., Cheung A.N.Y. and Ngan H.Y.S., AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity, PLoS ONE. 2013, 8: e53597.


Researcher : Chai J

Project Title:A pilot study on the combined use of letrozole, mifepristone and misoprostol in termination of first trimester pregnancy up to 9 weeks gestation
Investigator(s):Chai J, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2011
Completion Date:11/2012


Project Title:10th RCOG International Scientific Congress A randomized clinical trial comparing the sublingual and buccal routes of administration of misoprostol after mifepristone for medical abortions of up to 63 days gestation
Investigator(s):Chai J
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012


Project Title:A retrospective study on the cumulative live-birth rates in women with thyroid autoimmunity or subclinical hypothyroidism undergoing in-vitro fertilisation
Investigator(s):Chai J, Li RHW, Ho PC, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2012
Completion Date:05/2013


List of Research Outputs

Chai J., Wong C.Y. and Ho P.C., A randomized clinical trial comparing the short-term side effects of sublingual and buccal routes of misoprostol administration for medical abortions up to 63 days' gestation, Contraception. 2013, 87(4): 480-5.
Chai J., Evaluation of women with postmenopausal bleeding, Hong Kong Society for Ultrasound in Medicine, 10th AFSUMB Workshop. 2012.
Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, Clin Endocrinol (Oxf). 2013.
Chai J., Menstrual Disorder, HKU-Shenzhen Hospital CME programme. 2013.
Chai J. and Cheung V.Y.T., Postmenopausal Bleeding, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Nov/Dec2012: 257-263.
Chai J., Significance of abnormal thyroid function tests in subfertile patients, Update of reproductive medicine. 2012.


Researcher : Chan CP

List of Research Outputs

Kan A.S.Y., Lee C.P., Leung K.Y., Chan C.P., Tang M.H.Y. and Chan V.H.Y., Outcome of twin pregnancy after amniocentesis, Journal of Obstetrics and Gynaecology Research. 2012, 38(2): 376-382.


Researcher : Chan DW

Project Title:The functional impact of AMP-activated protein kinase gamma-2 (AMPK-g2)subunit expression on AMPK activity and oncogenesis in ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2011


Project Title:Functional Characterization of Has-miR-141, a Putative Oncogene in Promoting Anchorage-Independent Growth Ability of Ovarian Cancer Cells
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012


Project Title:Mechanistic and functional characterization of Bitter Melon extract (BME) and its active component, MAP30, in combating ovarian cancer chemoresistance
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


Project Title:Metabolism, Obesity and Obesity-associated Diseases ; The AMPK/TAK1 signaling axis is indispensable for controlling ovarian cancer cell metabolism and omental metastasis
Investigator(s):Chan DW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2013


List of Research Outputs

Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFkB activity is associated with the aggressiveness of ovarian cancers, 17th Research Postgraduate Symposium . 2012.
Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFkB activity is associated with the aggressiveness of ovarian cancers, 19th Hong Kong International Cancer Congress . 2012.
Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFB activity is associated with the aggressiveness of ovarian cancers, European Association of Cancer Research (EACR) 2012 Congress, Barcelona 7 -10 July 2012.
Chan D.W., Kwan H.T. and Ngan H.Y.S., AMPK activators inhibit cervical cancer cell growth through inhibition of Dvl3 mediated Wnt/b-catenin signaling, 2012 Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia. 2012.
Chan D.W., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer, Oncotarget. 2012, 3.
Chan D.W., Senior Editor, In: Robert Peng, American Journal of Clinical Cancer Research. Ivy Union Publishing LLC, 2012.
Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Chan D.W., Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells , Technology Seminar: Oligo for Custom Targeted NGS and Gene Silencing Genome Centre, HKU, co-organized with Integrated DNA Technologies Inc.. 2012.
Chan D.W. and Ngan H.Y.S., The AMP-activated protein kinase gamma-2 (AMPK-g2) subunit acts as a modifier of AMPK activity in ovarian cancer cells, CSH Asia / ICMS Joint Conference on Tumor Microenvironment, Suzhou Dushu Lake Conference Center No.299 Qiyue Road SIP/ Suzhou, Jiangsu Province, China. 2012.
Chan D.W., Cai C., Yung M.H. and Ngan H.Y.S., The AMPK/TAK1 signaling axis is indispensable for controlling ovarian cancer cell metabolism and omental metastasis, COLD SPRING HARBOR ASIA CONFERENCES: Metabolism, Obesity and Obesity-associated Diseases. Suzhou Dushu Lake Conference Center May 20-24, 2013. Suzhou, Jiangsu Province, China.. Suzhou, Jiangsu Province, China., 2013.
Chan D.W., The Macro World of MicroRNA, Departmental Seminar, Department of Obs. & Gyn., HKU. 2013.
Chan D.W. and Ngan H.Y.S., The prognostic and therapeutic potential of AMP-activated protein kinase in ovarian cancer, ASGO 2nd International Workshop on Gynecologic Oncology September 28 (Fri), 2012 Kyoto Tokyu Hotel, Japan . 2012.
Chan D.W., The prognostic and therapeutic potential of AMP-activated protein kinase in ovarian cancer, 香港大学学者报告会, Department of Biochemistry, Zhijiang University. 2012.
Kwan H.T., Chan D.W., Cai C., Mak S.L., Yung M.H., Leung T.H.Y., Wong G.W., Cheung A.N.Y. and Ngan H.Y.S., AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity, PLoS ONE. 2013, 8: e53597.
Lam K.Y., Ngan W.L., Leung M.H., Kwok C.T.D., Liu V.W.S., Chan D.W., Leung W.Y.G. and Yao K.M., FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c, Frontiers in Oncology. Frontiers, 2013, 3: 1-5.
Li C., Liu V.W.S., Chiu P.M., Chan D.W. and Ngan H.Y.S., Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications, BMC Cancer. BioMed Central, 2012, 12: 357.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of MicroRNA-199b-5p is associated with chemoresistance via JAG1-Notch1 in human epithelial ovarian cancer, 17th Research Postgraduate Symposium . 2012.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of MicroRNA-199b-5p is associated with chemoresistance via JAG1-Notch1 in human epithelial ovarian cancer, 19th Hong Kong International Cancer Congress . 2012.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of miR-199b-5p is associated with chemoresistance via Jagged1 in human ovarian cancer, European Association of Cancer Research (EACR) 2012 Congress, Barcelona 7 -10 July 2012.
Mak S.L., Chan D.W. and Ngan H.Y.S., The Upregulation of miR-141 Confers Anoikis Resistance through Targeting KLF12 in Ovarian Cancer Cells , 19th Hong Kong International Cancer Congress . 2012.
Mak S.L., Chan D.W. and Ngan H.Y.S., The upregulation of miR-141 confers anoikis resistance through targeting KLF12 in ovarian cancer cells, microRNA: Targets and Tools for Therapeutic Development. 3rd March - 5th March. Boston Marriott Cambridge, Cambridge, MA, USA. 2013.
Mak S.L., Chan D.W. and Ngan H.Y.S., miR-141 confers anoikis resistance of ovarian cancer cells by targeting KLF12, 17th Research Postgraduate Symposium . 2012.
Yung M.H. and Chan D.W., BME and MAP30 function as natural AMPK activators in inhibiting ovarian cancer cell growth , 香港大学学者报告会, Department of Biochemistry, Zhijiang University. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter Melon Extract (BME) used as Natural AMPK Activator in Inhibiting Ovarian Cancer Cells Growth, 17th Research Postgraduate Symposium. Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong.. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter Melon Extract (BME) used as Natural AMPK Activator in Inhibiting Ovarian Cancer Cells Growth, 19th Hong Kong International Cancer Congress Hong Kong Academy of Medicine, 99 Wong Chuk Hang Road, Aberdeen, Hong Kong.. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter melon extract (BME) used as natural AMPK activator in inhibiting ovarian cancer cells growth , CSH Asia / ICMS Joint Conference on Tumor Microenvironment Suzhou Dushu Lake Conference Center No.299 Qiyue Road SIP/ Suzhou, Jiangsu Province, China. 2012.


Researcher : Chan KKL

Project Title:Relationship between placental ratio and placental function
Investigator(s):Chan KKL, Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding for New Staff
Start Date:01/2003


Project Title:The effect of fulvestrant in epithelial ovarian cancer with differential estrogen receptor status in mice
Investigator(s):Chan KKL, Liu S, Tam KF, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2008


Project Title:Sixth International Symposium on Hormonal Oncogenesis USE OF HIGHLY SELECTIVE ESTROGEN RECEPTOR MODULATORS IN OVARIAN CANCER
Investigator(s):Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2010


Project Title:Evaluation of human epididymal secretory protein ( HE4 ) for monitoring for ovarian cancer recurrence
Investigator(s):Chan KKL, Liu S, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2011


Project Title:Characterization of the Platelet Isoform of Phosphofructokinase (PFKP) in ovarian cancer
Investigator(s):Chan KKL, Siu KY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


List of Research Outputs

Chan D.W., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer, Oncotarget. 2012, 3.
Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Chan K.K.L., Are we ready for HPV testing, XXIII Australian society for colposcopy and cervical pathology (ASCCP ) scientific meeting, Wellington, New Zealand. 2013.
Chan K.K.L., Cervical cancer screening guidelines: Dramatic changes in US and Europe, AOGIN interim meeting . Kunming 2013. 2013.
Chan K.K.L., Challenges in Quality assurance in colposcopy service, XXIII Australian society for colposcopy and cervical pathology (ASCCP ) scientific meeting. Wellington, New Zealand. 2013.
Chan K.K.L., Editorial Board - Journal of Paediatrics, Obstetrics and Gynaecology. 2012.
Chan K.K.L., Management of Glandular Abnormalities in cervical smears, XXIII Australian society for colposcopy and cervical pathology (ASCCP ) scientific meeting, Wellington, New Zealand. 2013.
Chan K.K.L., Pelvic mass risk assessment for ovarian cancer , Hong Kong International Cancer Conference. 2012.
Chan K.K.L., Chen C.A., Nam J.H., Ochiai K., Wilailak S., Choon A.T., Sabaratnam S., Hebbar S., Sicken J., Schodin B.A. and Sumpaico W.W., The use of HE4 in the prediction of ovarian cancer in Asian womenn with a pelvic mass, Gynecolgic Oncology. 2013, 128 (2): 239-44.
Chan K.K.L., Update on quadrivalent HPV vaccine, 2012.
Chan K.K.L., Update on quadrivalent HPV vaccine. Long term FU studies and vaccine impact, Lecture for University Health Service, Hong Kong. 2013.
Mak C.Y., Siu K.Y., Wong G.W., Chan K.K.L., Ngan H.Y.S. and Cheung A.N.Y., Dysregulated stemness-related genes in gynecological malignancies., Histology and histopathology. 2012, 27: 1121-1130.
Ye M., Lam W.W.T., Tsang J.W.H., Lee V.H.F., Soong I., Chan K.K.L., Lee C., Sze W.K., Yeo W., Suen J., Ho W.M. and Fielding R., Symptom clustering in different groups of cancer survivors (abstract and powerpoint presentation), The third Meeting of East Asian Psycho-Oncology Network (EAPON), 6-7 September 2012, Beijing. Beijing, Peking University, 2012, 18-19.
Ye M., Lam W.W.T., Tsang J.W.H., Lee V.H.F., Soong I., Chan K.K.L., Lee C., Sze W.K., Ng A., Yeo W., Suen J., Ho W.M. and Fielding R., Symptom clusters in cancer survivors in Hong Kong - a cluster analysis (abstract), 19th Hong Kong International Cancer Congress, 8-9 November 2012, Hong Kong. Hong Kong, LKS Faculty of Medicine, HKU, 2012, A72.


Researcher : Chan RWS

Project Title:The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometrium and Endometriosis.
Investigator(s):Chan RWS, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2013


List of Research Outputs

Chan R.W.S., Mak A.S.C., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S.T., Human Female Reproductive Tract Epithelial Cell Culture. In: Epithelial Cell Culture Protocols: Second Edition, Methods in Molecular Biology, vol. 945, Chapter 21., Scott H. Randell and M. Leslie Fulcher . 2013, 945: Ch21.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometriosis , 28th European Society of Human Reproduction and Embryology. 2012.
XIANG L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Nanoparticle tracking of a slow cycling stem-like subpopulation in human endometrium., 11th International Stem Cell Society. 2013.


Researcher : Chan YK

Project Title:Validating and examining SNPs identified from genome-wide scanning for disease susceptibility to HBV-related liver cancer in Chinese population
Investigator(s):Chan YK, Ng IOL, Wong CM
Department:Pathology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2010


List of Research Outputs

Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762.
Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318.


Researcher : Chan YY

List of Research Outputs

Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometriosis , 28th European Society of Human Reproduction and Embryology. 2012.


Researcher : Cheung KW

List of Research Outputs

Cheung K.W., Ngu S.F. and Lee C.P., Fetal Fibronectin Test On Chinese Women With Symptoms Of Preterm Labour: A Pilot Study, Hong Kong Medical Journal. 2013.


Researcher : Cheung SYC

List of Research Outputs

Cheung S.Y.C., Liu S., Ip P.P.C., Cheung A.N.Y. and Ngan H.Y.S., GENETIC AMPLIFICATION OF PIK3CA IN VULVAR SQUAMOUS CELL CARCINOMA, Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
Cheung S.Y.C., Chan C.H. and Ng E.H.Y., Stress and anxiety-depression levels following first-trimester miscarriage: a comparison between women who conceived naturally and women who conceived with assisted reproduction, British Journal of Obstetrics and Gynaecology (An International Journal of Obstetrics and Gynaecology) . 2013, 120: 1090-1097.


Researcher : Cheung VYT

List of Research Outputs

Chai J. and Cheung V.Y.T., Postmenopausal Bleeding, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Nov/Dec2012: 257-263.
Ngu S.F., Ko K.Y.J. and Cheung V.Y.T., Value of human chorionic gonadotropin levels in diagnosing cervical ectopic pregnancy, Acta Obstet Gynecol Scand. 2012.
Pun T.C., Ngu S.F., Seto T.Y.M. and Cheung V.Y.T., Second Trimester Termination of Pregnancy After Previous Classical Caesarean Section for Uterine Fibroid, RCOG World Congress 2013, Liverpool UK. 2013.
Seto T.Y.M., Ngu S.F., Cheung V.Y.T. and Pun T.C., Second Trimester Medical Abortion In A Woman With Prior Classical Caesarean Section And A Uterine Leiomyoma - A Case Report., Eur J Contracept Reprod Health Care. 2013.
Yung S.F., Cheung V.Y.T. and Chan G.S.W., Ovarian osteoma mimicking a teratoma on ultrasound, International Journal of Gynecology and Obstetrics. Elsevier Ireland Ltd, 2013, 121(Issue 3): 280-281.


Researcher : Chiu CN

Project Title:Control of human trophoblast invasion by CD147
Investigator(s):Chiu CN, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011
Completion Date:02/2013


Project Title:The roles of protein disulfide isomerase family A, member 3 (ERp57) and surface thiol/disulfide exchange in spermatozoa-zona pellucida binding and their association with fertilization in vitro.
Investigator(s):Chiu CN, Pang RTK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Defective sialyl-Lewis(x) expression on human zona pellucida as a potential cause of subfertilty
Investigator(s):Chiu CN, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2012


Project Title:28th Annual Meeting of the European Society of Human Reproduction and Embryology Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction
Investigator(s):Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2012
Completion Date:07/2012


Project Title:Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction
Investigator(s):Chiu CN, Pang RTK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
Chiu C.N., Editorial Board Member, Gynecology & Obstetrics. OMICS Publishing Group, Sunnyvale, CA., 2013.
Chiu C.N., Lam Y.F.E., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Lee C.L., Glycodelin-A modulates the functions of human macrophages: possible involvement in the maternal-fetal tolerogenic environment, In: American Society for Reproductive Immunology, 12th Congress of the International Society for Immunology Reproduction(ISIR), 28 May-1 June 2013, Boston, USA. USA, American Journal of Reproductive Immunology, 2013, Volume 69, Issue Supplement s2: 42.
Chiu C.N., Lee C.L., Zhao W., Huang W., Lam K.W., Ho P.C. and Yeung W.S.B., Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction, In: European Society of Human Reproduction and Embryology, 28th Annual Meeting of the European Society of Human Reproduction and Embryology . 2012, O-289.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Huang W., Yeung W.S.B., Ho P.C. and Chiu C.N., Sperm Fucosyltransferase-5 is involved in Spermatozoa-oviductal Epithelial Cell Interaction to Protect Human Spermatozoa from Oxidative Damage, 2013 Glycobiology Gordon Research Conference, Ventura, CA, March 3-8, 2013. .
Lam K.W., Pang R.T.K., Lee C.Y.L., Koistinen H., Seppala M., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line., Placenta. Elsevier, 2012, 33: 750-2.
Lee C.L., Lam E.Y., Lam K.K., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates interleukin-6 secretion from human monocytes and macrophages through L-selectin and extracellular signal-regulated kinases pathway., Journal of Biological Chemistry. 2012, 287(44): 36999-37009.
Lee C.L., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates interleukin-6 secretion via L-selectin binding on human monocytes and macrophages, Society for Reproduction and Fertility Annual Meeting 2012. .
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.
Yeung W.S.B., Chiu C.N., Dell A.N.N.E., Pang P.O.H.-.C.H.O.O., Khoo K.A.Y.-.H.O.O.I. and Clark G.A.R.Y., Human zona pellucida glycoproteins, their oligosaccharides, and uses thereof (WO/2013/012749), 2013.


Researcher : Chiu PM

List of Research Outputs

Li C., Liu V.W.S., Chiu P.M., Chan D.W. and Ngan H.Y.S., Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications, BMC Cancer. BioMed Central, 2012, 12: 357.


Researcher : Fong SW

List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
Lee C.Y.L., PENG Q., Fong S.W., CHEN C.H., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways, PLoS One. 2012, 7(9): e45633.


Researcher : HOU YCD

List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.


Researcher : HUANG W

List of Research Outputs

Chiu C.N., Lee C.L., Zhao W., Huang W., Lam K.W., Ho P.C. and Yeung W.S.B., Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction, In: European Society of Human Reproduction and Embryology, 28th Annual Meeting of the European Society of Human Reproduction and Embryology . 2012, O-289.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Huang W., Yeung W.S.B., Ho P.C. and Chiu C.N., Sperm Fucosyltransferase-5 is involved in Spermatozoa-oviductal Epithelial Cell Interaction to Protect Human Spermatozoa from Oxidative Damage, 2013 Glycobiology Gordon Research Conference, Ventura, CA, March 3-8, 2013. .


Researcher : Ho PC

Project Title:Studies on the effects of ulipristal on sperm functions
Investigator(s):Ho PC, Ng EHY, Li RHW, Yeung WSB, Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2012


List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
Chai J., Wong C.Y. and Ho P.C., A randomized clinical trial comparing the short-term side effects of sublingual and buccal routes of misoprostol administration for medical abortions up to 63 days' gestation, Contraception. 2013, 87(4): 480-5.
Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, Clin Endocrinol (Oxf). 2013.
Chan C.H.Y., Chan C.L.W., Ng E.H.Y., Ho P.C., Lee G.L. and Hui Choi W.H., Incorporating spirituality in psychosocial group intervention for women undergoing in vitro fertilization: A prospective randomized controlled study, Psychology and Psychotherapy. 2012, 85(4): 356-373.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Ho P.C., Anti-mullerian hormone in Reproductive Medicine, The Scientific Meeting of South Asia Federation of Obstetrics and Gynaecology, Agra, India, March 1-3, 2013. 2013.
Ho P.C., Clinical use of Misoprostol in Gynaecology , The FIGO World Congress of Obstetrics and Gynaecology in Rome, Italy, October 7-12, 2012. 2012.
Ho P.C., Clinical use of misoprostol in Gynaecology, The Annual Scientific Meeting of the Sri Lanka College of Obstetricians and Gynaecologists, October 19-22, 2012. 2012.
Ho P.C., Current Gonadotrphin use in Assisted reproduction, Masterclass IVF as Faculty, held at Hyatt Regency, Mumbai, India on September 8-9, 2012. 2012.
Ho P.C., Current use of gonadotrophins in assisted reproduction, Master Class IVF Meeting in Mumbai, India, September 8-12, 2012. 2012.
Ho P.C., Director of Editorial Board in Obstetrics and Gynaecology, Journal of Paediatrics, Obstetrics and Gynaecology, 1997 till now. 2013.
Ho P.C., IVF in PCOS, Masterclass IVF as Faculty, held at Hyatt Regency, Mumbai, India on September 8-9, 2012. 2012.
Ho P.C., Lecture on "Role of ovarian reserve markers in assisted reproduction", 7th Annual Scientific Meeting of Chinese Society of Reproductive Medicine, in Shenyang, China, May 10-12, 2013. 2013.
Ho P.C., Lecture on "Update on medical abortion", The Second International Congress on Women's Health and Unsafe Abortion held in Bangkok, Thailand, January 22-25, 2013. 2013.
Ho P.C., Levonorgestrel (LNG)-development of hormonal methods of emergency contraception, The European Journal of Contraception and Reproductive Health Care. 2013, 18 (Supplement 1): S44-S45.
Ho P.C., Levonorgestrel: Development of hormonal methods of emergency contraception, The First Global Conference on Contraception, Sexual and Reproductive Health, held in Copenhagen, Denmark, May 22-24, 2013. 2013.
Ho P.C., Member of Editorial Board, Chinese Journal of Obstetrics and Gynaecology. 2013.
Ho P.C., Member of Editorial Board, Clinical Obstetrics and Gynaecology (Bailliere Tindall). 2013.
Ho P.C., Member of Editorial Board, Journal of Practical Obstetrics and Gynaecology. 2013.
Ho P.C., Member of Editorial Board, Journal of Reproductive Medicine (China). 2013.
Ho P.C., Member of the Advisory Editorial Board, Asia Oceania Journal of Obstetrics and Gynaecology, 1994 till now. 2013.
Ho P.C., PCOS: Management beyond infertility, Presented at All India Congress in Obstetrics and Gynaecology held in Mumbai, India, January 18-19, 2013. 2013.
Ho P.C., Preparation of recipients for oocyte donation, Master Class IVF Meeting in Mumbai, India, September 8-12, 2012. 2012.
Ho P.C., Preparation of recipients, Masterclass IVF as Faculty, held at Hyatt Regency, Mumbai, India on September 8-9, 2012. 2012.
Ho P.C., Protection of fertility in China, The First Global Conference on Contraception, Sexual and Reproductive Health, held in Copenhagen, Denmark, May 22-24, 2013. 2013.
Ho P.C., Reviewer for "American Journal of Obstetrics and Gynaecology". 2013.
Ho P.C., Reviewer for "Obstetrics and Gynaecology". 2013.
Ho P.C. and Lo S.S.T., The profile of women who seek emergency contraception from the family planning service, Hong Kong Medical Journal, August 2012. 2012, 18(4): 299-303.
Ho P.C., Update on Medical Abortion, The Scientific Meeting of South Asia Federation of Obstetrics and Gynaecology, Agra, India, March 1-3, 2013. 2013.
Lam K.W., Pang R.T.K., Lee C.Y.L., Koistinen H., Seppala M., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line., Placenta. Elsevier, 2012, 33: 750-2.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Luteal phase support does not improve the clinical pregnancy rate of natural cycle frozen-thawed embryo transfer: a retrospective analysis, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 169(1): 50-53.
Lee V.C.Y., Ng E.H.Y. and Ho P.C., Male infertility, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Sept-Oct: 213-220.
Li R.H.W., Ng E.H.Y., Wong B.P.C., Anderson R.A., Ho P.C. and Yeung W.S.B., Correlation between three assay systems for anti-Müllerian hormone (AMH) determination, Journal of Assisted Reproduction and Genetics. 2012, 29: 1443-1446.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of Baseline Antral Follicle Count and Anti-Mullerian Hormone in Prediction of Cumulative Live Birth in the First In Vitro Fertilisation Cycle: A Retrospective Cohort Analysis, PLos One. 2013, 8(4): e61095.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate may contribute to contraceptive action by its effects on tubal function, The European Journal of Contraception and Reproductive Health Care. 2013, 18 (Supplement 1): S193-S194.
Tiwari A.F.Y., Fong D.Y.T., Chan C.H. and Ho P.C., Factors Mediating the Relationship between Intimate Partner Violence and Chronic Pain in Chinese Women. , Journal of Interpersonal Violence. 2012.
Yeung T.W.Y., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized double-blinded placebo-controlled trial on the effect of dehydroepiandrosterone for 16 weeks on ovarian response markers in women with primary ovarian insufficiency, Journal of Clinical Endocrinology and Metabolism. 2013, 98(1): 380-388.


Researcher : Huang W

List of Research Outputs

Chiu C.N., Lee C.L., Zhao W., Huang W., Lam K.W., Ho P.C. and Yeung W.S.B., Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction, In: European Society of Human Reproduction and Embryology, 28th Annual Meeting of the European Society of Human Reproduction and Embryology . 2012, O-289.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Huang W., Yeung W.S.B., Ho P.C. and Chiu C.N., Sperm Fucosyltransferase-5 is involved in Spermatozoa-oviductal Epithelial Cell Interaction to Protect Human Spermatozoa from Oxidative Damage, 2013 Glycobiology Gordon Research Conference, Ventura, CA, March 3-8, 2013. .


Researcher : Hui PW

Project Title:31st British International Congress of Obstetrics & Gynaecology 2007 A rare cause of Thrombocytopenia in Pregnancy-EDTA-dependent Pseudothrombocytopenia
Investigator(s):Hui PW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2007


List of Research Outputs

Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH evaluation for prenatal diagnosis in Hong Kong, Poster presentation (P1-9) in 16th International Conference on Prenatal Diagnosis and Therapy, 3-6 June, Miami, USA. Prenat Diagn 2012;32(Supp. 1):S1 . 2012.


Researcher : Hui WY

List of Research Outputs

Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.


Researcher : Kan ASY

List of Research Outputs

Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Kan A.S.Y., Lee C.P., Leung K.Y., Chan C.P., Tang M.H.Y. and Chan V.H.Y., Outcome of twin pregnancy after amniocentesis, Journal of Obstetrics and Gynaecology Research. 2012, 38(2): 376-382.
Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH evaluation for prenatal diagnosis in Hong Kong, Poster presentation (P1-9) in 16th International Conference on Prenatal Diagnosis and Therapy, 3-6 June, Miami, USA. Prenat Diagn 2012;32(Supp. 1):S1 . 2012.


Researcher : Kan SYA

List of Research Outputs

Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318.


Researcher : Ko KYJ

List of Research Outputs

Ngu S.F., Ko K.Y.J. and Cheung V.Y.T., Value of human chorionic gonadotropin levels in diagnosing cervical ectopic pregnancy, Acta Obstet Gynecol Scand. 2012.


Researcher : Kwan HT

List of Research Outputs

Chan D.W., Kwan H.T. and Ngan H.Y.S., AMPK activators inhibit cervical cancer cell growth through inhibition of Dvl3 mediated Wnt/b-catenin signaling, 2012 Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia. 2012.
Kwan H.T., Chan D.W., Cai C., Mak S.L., Yung M.H., Leung T.H.Y., Wong G.W., Cheung A.N.Y. and Ngan H.Y.S., AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity, PLoS ONE. 2013, 8: e53597.


Researcher : LEUNG ON

List of Research Outputs

LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., MicroRNA-135a regulates cervical cancer transformation and progression through ß-catenin via a SIAH1-dependent ubiquitin-proteosomal pathway, The 19th Hong Kong International Cancer Congress. 2012.
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., Role of microRNA-135a in cervical cancer transformation and development., The 17th Research Postgraduate Symposium. 2012.
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.


Researcher : LEUNG TW

List of Research Outputs

Chung K.F., Yeung W.F., Zhang Z., Yung K.P., Man M.S.C., Lee C.P., Lam S.K., Leung T.W., Leung K.Y., Eric Z.T.C. and Wong V.C.W., Randomized non-invasive sham-controlled pilot trial of electroacupuncture for postpartum depression, Journal of Affective Disorders. 2012, 142: 115-121.
LEUNG T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN), 28th International Papillomavirus Conference, San Juan, Puerto Rico, Nov 30 – Dec 6, 2012. . 2012.
Leung T.W., Liu S., Chan A.N.H., Cheung A.N.Y. and Ngan H.Y.S., EXPRESSION OF NOTCH 1 PROTEIN IN CERVICAL CANCER AND CERVICAL PREMALIGNANT LESIONS AND ITS CORRELATION WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION AND CLINICAL PARAMETERS , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.


Researcher : Lam KW

List of Research Outputs

Chiu C.N., Lee C.L., Zhao W., Huang W., Lam K.W., Ho P.C. and Yeung W.S.B., Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction, In: European Society of Human Reproduction and Embryology, 28th Annual Meeting of the European Society of Human Reproduction and Embryology . 2012, O-289.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Lam K.W., Pang R.T.K., Lee C.Y.L., Koistinen H., Seppala M., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line., Placenta. Elsevier, 2012, 33: 750-2.
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.


Researcher : Lam KW

List of Research Outputs

Chiu C.N., Lee C.L., Zhao W., Huang W., Lam K.W., Ho P.C. and Yeung W.S.B., Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction, In: European Society of Human Reproduction and Embryology, 28th Annual Meeting of the European Society of Human Reproduction and Embryology . 2012, O-289.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Lam K.W., Pang R.T.K., Lee C.Y.L., Koistinen H., Seppala M., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line., Placenta. Elsevier, 2012, 33: 750-2.
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.


Researcher : Lam SK

List of Research Outputs

Chung K.F., Yeung W.F., Zhang Z., Yung K.P., Man M.S.C., Lee C.P., Lam S.K., Leung T.W., Leung K.Y., Eric Z.T.C. and Wong V.C.W., Randomized non-invasive sham-controlled pilot trial of electroacupuncture for postpartum depression, Journal of Affective Disorders. 2012, 142: 115-121.


Researcher : Lam YFE

List of Research Outputs

Chiu C.N., Lam Y.F.E., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Lee C.L., Glycodelin-A modulates the functions of human macrophages: possible involvement in the maternal-fetal tolerogenic environment, In: American Society for Reproductive Immunology, 12th Congress of the International Society for Immunology Reproduction(ISIR), 28 May-1 June 2013, Boston, USA. USA, American Journal of Reproductive Immunology, 2013, Volume 69, Issue Supplement s2: 42.


Researcher : Lam YH

Project Title:11th World Congress on Ultrasound in Obstetrics and Gynecology Integrated First and Second Trimester Screening for Down Syndrome
Investigator(s):Lam YH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2001




Researcher : Lao TTH

Project Title:The First Congress on Obstetrics, Gynecology & Infertility Does Impaired Glucose Tolerance Impact on Pregnancy Outcome?
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/1999


Project Title:Dietary caloric intake and the development of gestational diabetes mellitus in at-risk Chinese women
Investigator(s):Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:The role of adiponectin in the development of gestational diabetes mellitus and its effect on pregnancy outcome
Investigator(s):Lao TTH, Lam KSL, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Elevated TNF-α in gestational diabetes mellitus-cause or consequence?
Investigator(s):Lao TTH, Leung WC, Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The relationship between the antioxidant defense system with the development of gestational diabetes mellitus and its complications in the Chinese population.
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2005




Researcher : Lau ETK

List of Research Outputs

Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762.
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318.
Tang M.H.Y., Lau E.T.K., Tan T.Y., Chung B.H.Y. and Shek N.W.M., Prenatal Diagnosis of Agenesis of the Corpus Callosum and Cerebellar Vermian Hypoplasia Associated with a Microdeletion on Chromosome 1p32: Decision Minor revision, Case Reports in Perinatal Medicine. 2013, 2;1-2: 39-45.
Tsang J.S., Tong D.K.H., Chung B.H.Y., Tang M.H.Y., Lau E.T.K., Chan G.C.F. and Law S.Y.K., Alport's syndrome: case of a giant esophageal tumor [Doi:10.1007/s10388-012-0355-3], Esophagus. Springer, 2013, 10: 114-117.


Researcher : Lau EYL

List of Research Outputs

Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of Baseline Antral Follicle Count and Anti-Mullerian Hormone in Prediction of Cumulative Live Birth in the First In Vitro Fertilisation Cycle: A Retrospective Cohort Analysis, PLos One. 2013, 8(4): e61095.


Researcher : Lee CKF

Project Title:Functional characterization of VAD1.3, a novel acrosome-specific protein by conditional tissue-specific gene inactivation
Investigator(s):Lee CKF, Cheah KSE, Yeung WSB, Luk JMC, Lee NPY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:Environmental Screening, Computational and Biological Characterization of Endocrine Disruptors, in Respect to Receptor Binding, Embryo and Gonad Physiology
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2009


Project Title:Role(s) of Glycodelin on Implantation
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011
Completion Date:08/2012


Project Title:Study of Electroacupuncture on modulating rodent spermatogenesis after scrotal heat treatment
Investigator(s):Lee CKF, Yeung WSB, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2012


Project Title:SSR's 45th Annual Meeting and the 18th Ovarian Workshop ; VAD1.2 knockout mice exhibit flagella defect and impaired fertility
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2012


Project Title:Functional roles of human chorionic gonadotropin (hCG) and Wnt-signaling molecules on tubal ectopic pregnancy
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2013


List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., The estrogen-regulated Let-7a plays a pivotal role during blastocyst activation via its effect on Vav3, The 7th International Huaxia Congress of Endocrinology, Hong Kong. 2012.
Chan R.W.S., Mak A.S.C., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S.T., Human Female Reproductive Tract Epithelial Cell Culture. In: Epithelial Cell Culture Protocols: Second Edition, Methods in Molecular Biology, vol. 945, Chapter 21., Scott H. Randell and M. Leslie Fulcher . 2013, 945: Ch21.
LIU J., Lee C.K.F., Sze C.W., Tong Y., Tang S.C.W., Ng T.B. and Zhang Y., Experimental studies on intestinal absorption and bioavailability of traditional Chinese medicines: Recent progress and implication for quality control., In: LIU JY, LEE KF, SZE CW, TONG Y, TANG CW, NG TB, YB ZHANG*. , 11th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 21-23, 2012, Macau, China.. 2012.
LIU J., Lee C.K.F., Sze C.W., Tong Y., Tang S.C.W., Ng T.B. and Zhang Y., Experimental studies on intestinal absorption and bioavailability of traditional Chinese medicines: Recent progress and implication for quality control, In: Liu JY, KF Lee, Sze CW, Tong Y, Tang CW, Ng TB, Zhang YB*, Journal of pharmacy and pharmacology. 2013, 65(5): 621-33.
Lee C.Y.L., PENG Q., Fong S.W., CHEN C.H., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways, PLoS One. 2012, 7(9): e45633.
Liu J.I.N.G.-.Y.I., Lee C.K.F., Sze C.W., Tong Y., Tang S.C.W., Ng T.Z.I. .U.N. and Zhang Y., Intestinal absorption and bioavailability of traditional Chinese medicines: a review of recent experimental progress and implication for quality control, Journal of pharmacy and pharmacology. 2012, 65 (5): 621-633.
SONG T., Lee C.K.F., Sze C.W., Tong Y., Tang S.C.W., Leung G.P.H. and Zhang Y., A Novel Method for Quality Control of Chinese Medicines in vivo/vitro. , In: Song TH, Calvin Lee KF, Stephen Sze CW, Tong Y, Sydney Tang CW, George Leung PH, Kalin Zhang YB*., 11st Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 21-23, 2012, Macao, China. . 2012.
SONG T., Lee C.K.F. and Zhang Y., Capillary electrophoresis combined with polypropylene hollow fiber liquid-liquid-liquid microextraction to determine alkaloids., In: Song TH, Calvin KF Lee, Kalin YB Zhang*., The 8th International Postgraduates Symposium on Chinese Medicine. 16th August 2012 in Hong Kong Conventionand Exhibition Center. Organized by Committee of Modernized Chinese Medicine (ICMCM).. 2012.


Researcher : Lee CL

Project Title:Society for Reproduction and Fertility Conference 2012 Glycodelin-A stimulates interleukin-6 secretion via L-selectin binding on human monocytes and macrophages
Investigator(s):Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2012
Completion Date:07/2012


List of Research Outputs

Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometriosis , 28th European Society of Human Reproduction and Embryology. 2012.
Chiu C.N., Lam Y.F.E., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Lee C.L., Glycodelin-A modulates the functions of human macrophages: possible involvement in the maternal-fetal tolerogenic environment, In: American Society for Reproductive Immunology, 12th Congress of the International Society for Immunology Reproduction(ISIR), 28 May-1 June 2013, Boston, USA. USA, American Journal of Reproductive Immunology, 2013, Volume 69, Issue Supplement s2: 42.
Chiu C.N., Lee C.L., Zhao W., Huang W., Lam K.W., Ho P.C. and Yeung W.S.B., Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction, In: European Society of Human Reproduction and Embryology, 28th Annual Meeting of the European Society of Human Reproduction and Embryology . 2012, O-289.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Lee C.L., Lam E.Y., Lam K.K., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates interleukin-6 secretion from human monocytes and macrophages through L-selectin and extracellular signal-regulated kinases pathway., Journal of Biological Chemistry. 2012, 287(44): 36999-37009.
Lee C.L., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates interleukin-6 secretion via L-selectin binding on human monocytes and macrophages, Society for Reproduction and Fertility Annual Meeting 2012. .
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.


Researcher : Lee CP

List of Research Outputs

Cheung K.W., Ngu S.F. and Lee C.P., Fetal Fibronectin Test On Chinese Women With Symptoms Of Preterm Labour: A Pilot Study, Hong Kong Medical Journal. 2013.
Chung K.F., Yeung W.F., Zhang Z., Yung K.P., Man M.S.C., Lee C.P., Lam S.K., Leung T.W., Leung K.Y., Eric Z.T.C. and Wong V.C.W., Randomized non-invasive sham-controlled pilot trial of electroacupuncture for postpartum depression, Journal of Affective Disorders. 2012, 142: 115-121.
Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Kan A.S.Y., Lee C.P., Leung K.Y., Chan C.P., Tang M.H.Y. and Chan V.H.Y., Outcome of twin pregnancy after amniocentesis, Journal of Obstetrics and Gynaecology Research. 2012, 38(2): 376-382.
Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH evaluation for prenatal diagnosis in Hong Kong, Poster presentation (P1-9) in 16th International Conference on Prenatal Diagnosis and Therapy, 3-6 June, Miami, USA. Prenat Diagn 2012;32(Supp. 1):S1 . 2012.


Researcher : Lee CYL

List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
Chong T.Y.I., Lee C.Y.L., Shiu S.Y.W. and Yao K.M., Using small molecules to induce the progressive differentiation of hESCs into pancreatic β-cell-like progenitors, 17th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, December 12, 2012.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Lam K.W., Pang R.T.K., Lee C.Y.L., Koistinen H., Seppala M., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line., Placenta. Elsevier, 2012, 33: 750-2.
Lee C.Y.L., PENG Q., Fong S.W., CHEN C.H., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways, PLoS One. 2012, 7(9): e45633.


Researcher : Lee VCY

List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, Clin Endocrinol (Oxf). 2013.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Luteal phase support does not improve the clinical pregnancy rate of natural cycle frozen-thawed embryo transfer: a retrospective analysis, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 169(1): 50-53.
Lee V.C.Y., Ng E.H.Y. and Ho P.C., Male infertility, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Sept-Oct: 213-220.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of Baseline Antral Follicle Count and Anti-Mullerian Hormone in Prediction of Cumulative Live Birth in the First In Vitro Fertilisation Cycle: A Retrospective Cohort Analysis, PLos One. 2013, 8(4): e61095.
Yeung T.W.Y., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized double-blinded placebo-controlled trial on the effect of dehydroepiandrosterone for 16 weeks on ovarian response markers in women with primary ovarian insufficiency, Journal of Clinical Endocrinology and Metabolism. 2013, 98(1): 380-388.


Researcher : Leung CY

List of Research Outputs

Liu S., Ng E.K.O., Leung C.Y., Cheung A.N.Y., Kwong A. and Ngan H.Y.S., ALTERED MICRORNA EXPRESSION ASSOCIATED WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION IN CERVICAL CANCER , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
Liu S., Ng E.K.O., Leung C.Y., Cheung A.N.Y., Kwong A. and Ngan H.Y.S., Aberrant miRNA expressions associated with Human Papillomavirus (HPV) infection contribute to cervical carcinogenesis , 28th International Papillomavirus Conference, Puerto Rico, Nov.30-Dec. 6, 2012.


Researcher : Leung KY

List of Research Outputs

Chung K.F., Yeung W.F., Zhang Z., Yung K.P., Man M.S.C., Lee C.P., Lam S.K., Leung T.W., Leung K.Y., Eric Z.T.C. and Wong V.C.W., Randomized non-invasive sham-controlled pilot trial of electroacupuncture for postpartum depression, Journal of Affective Disorders. 2012, 142: 115-121.
Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Kan A.S.Y., Lee C.P., Leung K.Y., Chan C.P., Tang M.H.Y. and Chan V.H.Y., Outcome of twin pregnancy after amniocentesis, Journal of Obstetrics and Gynaecology Research. 2012, 38(2): 376-382.
Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH evaluation for prenatal diagnosis in Hong Kong, Poster presentation (P1-9) in 16th International Conference on Prenatal Diagnosis and Therapy, 3-6 June, Miami, USA. Prenat Diagn 2012;32(Supp. 1):S1 . 2012.


Researcher : Leung THY

Project Title:Identification and characterization of cancer stem cells in cervical cancer
Investigator(s):Leung THY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2011
Completion Date:08/2012


Project Title:Clinical correlation of DNp73/C35/HER2 and their cooperative effects in ovarian cancer.
Investigator(s):Leung THY, Ngan HYS, Cheung ANY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2013


List of Research Outputs

Chan D.W., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer, Oncotarget. 2012, 3.
Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Kwan H.T., Chan D.W., Cai C., Mak S.L., Yung M.H., Leung T.H.Y., Wong G.W., Cheung A.N.Y. and Ngan H.Y.S., AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity, PLoS ONE. 2013, 8: e53597.


Researcher : Leung TW

List of Research Outputs

Chung K.F., Yeung W.F., Zhang Z., Yung K.P., Man M.S.C., Lee C.P., Lam S.K., Leung T.W., Leung K.Y., Eric Z.T.C. and Wong V.C.W., Randomized non-invasive sham-controlled pilot trial of electroacupuncture for postpartum depression, Journal of Affective Disorders. 2012, 142: 115-121.
LEUNG T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN), 28th International Papillomavirus Conference, San Juan, Puerto Rico, Nov 30 – Dec 6, 2012. . 2012.
Leung T.W., Liu S., Chan A.N.H., Cheung A.N.Y. and Ngan H.Y.S., EXPRESSION OF NOTCH 1 PROTEIN IN CERVICAL CANCER AND CERVICAL PREMALIGNANT LESIONS AND ITS CORRELATION WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION AND CLINICAL PARAMETERS , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.


Researcher : Leung TW

List of Research Outputs

Chung K.F., Yeung W.F., Zhang Z., Yung K.P., Man M.S.C., Lee C.P., Lam S.K., Leung T.W., Leung K.Y., Eric Z.T.C. and Wong V.C.W., Randomized non-invasive sham-controlled pilot trial of electroacupuncture for postpartum depression, Journal of Affective Disorders. 2012, 142: 115-121.
LEUNG T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN), 28th International Papillomavirus Conference, San Juan, Puerto Rico, Nov 30 – Dec 6, 2012. . 2012.
Leung T.W., Liu S., Chan A.N.H., Cheung A.N.Y. and Ngan H.Y.S., EXPRESSION OF NOTCH 1 PROTEIN IN CERVICAL CANCER AND CERVICAL PREMALIGNANT LESIONS AND ITS CORRELATION WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION AND CLINICAL PARAMETERS , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.


Researcher : Leung WC

List of Research Outputs

Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH evaluation for prenatal diagnosis in Hong Kong, Poster presentation (P1-9) in 16th International Conference on Prenatal Diagnosis and Therapy, 3-6 June, Miami, USA. Prenat Diagn 2012;32(Supp. 1):S1 . 2012.


Researcher : Li C

List of Research Outputs

Li C., Liu V.W.S., Chiu P.M., Chan D.W. and Ngan H.Y.S., Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications, BMC Cancer. BioMed Central, 2012, 12: 357.


Researcher : Li RHW

Project Title:An in vitro study of endocrine factors regulating expression of anti-Mullerian hormone in human granulosa cells
Investigator(s):Li RHW, Yeung WSB, Cheung ANY, Ng EHY, Ho PC, O WS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013


Project Title:First Global Conference on Contraception, Reproductive and Sexual Health ; Ulipristal acetate may contribute to contraceptive action by its effects on tubal function
Investigator(s):Li RHW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2013


List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, Clin Endocrinol (Oxf). 2013.
Chung B.H.Y., Luk H.M., Lo I.F.M., Lam S.T.S. and Li R.H.W., A second report of p.Pro986Leu variant in COL2A1 - phenotypic overlap with SEDC and other forms of type II collagenopathies, American Journal of Medical Genetics (Part A). 2013, 161A: 918-920.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Luteal phase support does not improve the clinical pregnancy rate of natural cycle frozen-thawed embryo transfer: a retrospective analysis, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 169(1): 50-53.
Li R.H.W., Approach to the infertile couple, 7th International Huaxia Congress of Endocrinology. 2012.
Li R.H.W., Ng E.H.Y., Wong B.P.C., Anderson R.A., Ho P.C. and Yeung W.S.B., Correlation between three assay systems for anti-Müllerian hormone (AMH) determination, Journal of Assisted Reproduction and Genetics. 2012, 29: 1443-1446.
Li R.H.W. and Ng E.H.Y., Management of anovulatory infertility, Best Practice & Research Clinical Obstetrics & Gynaecology. 2012, 26: 757-768.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of Baseline Antral Follicle Count and Anti-Mullerian Hormone in Prediction of Cumulative Live Birth in the First In Vitro Fertilisation Cycle: A Retrospective Cohort Analysis, PLos One. 2013, 8(4): e61095.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate may contribute to contraceptive action by its effects on tubal function, The European Journal of Contraception and Reproductive Health Care. 2013, 18 (Supplement 1): S193-S194.
Li R.H.W., Vitamin D and polycystic ovary syndrome, The Symposium of Polycystic Ovary Syndrome. 2013.
O W.S., Li R.H.W., Liao S., Ho J.C.M., Ng E.H.Y., Yeung W.S.B., Cheung A.N.Y. and Tang F., Adrenomedullin as a biomarker for tubal ectopic pregnancy – new evidence from adrenomedullin function in the nasal ciliary epithelium. Society for Reproduction and fertility, Edinburgh, United Kingdom, #O019, July 2012.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100(2): 459-463.
Yeung T.W.Y., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized double-blinded placebo-controlled trial on the effect of dehydroepiandrosterone for 16 weeks on ovarian response markers in women with primary ovarian insufficiency, Journal of Clinical Endocrinology and Metabolism. 2013, 98(1): 380-388.


Researcher : Liao S

List of Research Outputs

Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate may contribute to contraceptive action by its effects on tubal function, The European Journal of Contraception and Reproductive Health Care. 2013, 18 (Supplement 1): S193-S194.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100(2): 459-463.


Researcher : Liu S

List of Research Outputs

Cheung S.Y.C., Liu S., Ip P.P.C., Cheung A.N.Y. and Ngan H.Y.S., GENETIC AMPLIFICATION OF PIK3CA IN VULVAR SQUAMOUS CELL CARCINOMA, Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
LEUNG T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN), 28th International Papillomavirus Conference, San Juan, Puerto Rico, Nov 30 – Dec 6, 2012. . 2012.
Leung T.W., Liu S., Chan A.N.H., Cheung A.N.Y. and Ngan H.Y.S., EXPRESSION OF NOTCH 1 PROTEIN IN CERVICAL CANCER AND CERVICAL PREMALIGNANT LESIONS AND ITS CORRELATION WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION AND CLINICAL PARAMETERS , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
Liu S., Ng E.K.O., Leung C.Y., Cheung A.N.Y., Kwong A. and Ngan H.Y.S., ALTERED MICRORNA EXPRESSION ASSOCIATED WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION IN CERVICAL CANCER , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
Liu S., Ng E.K.O., Leung C.Y., Cheung A.N.Y., Kwong A. and Ngan H.Y.S., Aberrant miRNA expressions associated with Human Papillomavirus (HPV) infection contribute to cervical carcinogenesis , 28th International Papillomavirus Conference, Puerto Rico, Nov.30-Dec. 6, 2012.
Zhang P., Liu S. and Ngan H.Y.S., TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells, In: Wael El-Rifai, PLoS One. 2012, 7(8).


Researcher : Liu VWS

List of Research Outputs

Lam K.Y., Ngan W.L., Leung M.H., Kwok C.T.D., Liu V.W.S., Chan D.W., Leung W.Y.G. and Yao K.M., FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c, Frontiers in Oncology. Frontiers, 2013, 3: 1-5.
Li C., Liu V.W.S., Chiu P.M., Chan D.W. and Ngan H.Y.S., Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications, BMC Cancer. BioMed Central, 2012, 12: 357.


Researcher : Liu W

Project Title:World Congress on Reproductive Biology Involvement of let-7 microRNA in the regulation of embryo implantation in mice
Investigator(s):Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2011


List of Research Outputs

CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., The estrogen-regulated Let-7a plays a pivotal role during blastocyst activation via its effect on Vav3, The 7th International Huaxia Congress of Endocrinology, Hong Kong. 2012.


Researcher : Liu X

List of Research Outputs

Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of MicroRNA-199b-5p is associated with chemoresistance via JAG1-Notch1 in human epithelial ovarian cancer, 17th Research Postgraduate Symposium . 2012.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of MicroRNA-199b-5p is associated with chemoresistance via JAG1-Notch1 in human epithelial ovarian cancer, 19th Hong Kong International Cancer Congress . 2012.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of miR-199b-5p is associated with chemoresistance via Jagged1 in human ovarian cancer, European Association of Cancer Research (EACR) 2012 Congress, Barcelona 7 -10 July 2012.


Researcher : Lu X

List of Research Outputs

Mak C.Y., Lee L., Siu K.Y., Wong G.W., Lu X., Ngan H.Y.S., Wong E.S. and Cheung A.N.Y., Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation , Carcinogenesis. 2013, June 2013.


Researcher : Mak SL

List of Research Outputs

Chan D.W., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer, Oncotarget. 2012, 3.
Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Kwan H.T., Chan D.W., Cai C., Mak S.L., Yung M.H., Leung T.H.Y., Wong G.W., Cheung A.N.Y. and Ngan H.Y.S., AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity, PLoS ONE. 2013, 8: e53597.
Mak S.L., Chan D.W. and Ngan H.Y.S., The Upregulation of miR-141 Confers Anoikis Resistance through Targeting KLF12 in Ovarian Cancer Cells , 19th Hong Kong International Cancer Congress . 2012.
Mak S.L., Chan D.W. and Ngan H.Y.S., The upregulation of miR-141 confers anoikis resistance through targeting KLF12 in ovarian cancer cells, microRNA: Targets and Tools for Therapeutic Development. 3rd March - 5th March. Boston Marriott Cambridge, Cambridge, MA, USA. 2013.
Mak S.L., Chan D.W. and Ngan H.Y.S., miR-141 confers anoikis resistance of ovarian cancer cells by targeting KLF12, 17th Research Postgraduate Symposium . 2012.


Researcher : Ng EHY

Project Title:The 17th IFFS World Congress on Fertility and Sterility 1) Measurement of Serum CA-125 Concentrations Does not Improve the Value of Chlamydia Trachomatis Antibody (CAT) in Predicting Tubal Pathology at Laparoscopy 2) A Comparison of the Pain Levels During Egg Collection and Postoperative Side Effects Using Paracervical Block with and without Conscious Sedation
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2001


Project Title:Comparison of the prevalence of polycystic ovary only and polycystic ovary syndrome between two different ethnic populations
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:The role of anti-Müllerian hormone in the prediction of livebirth rate and cumulative livebirth rate during in vitro fertilization treatment
Investigator(s):Ng EHY, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2006


Project Title:Role of Sirt1 in generation of mouse induced pluripotent stem cells
Investigator(s):Ng EHY, Lee CKF, Lee CYL, Ng RK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Mechanisms of delayed ovulation following Ulipristal used as emergency contraception
Investigator(s):Ng EHY, Li RHW, O WS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:04/2013


Project Title:Control of human decidual macrophage differentiation by glycodelin-A
Investigator(s):Ng EHY, Chiu CN, Lee CL, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2012


Project Title:Annual meeting of The American Society for Reproductive Medicine; Uterine and ovarian blood flow in the predication of pregnancy in infertile patients
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2012


List of Research Outputs

Broer S.L., van Disseldorp J., Broeze K.A., Dolleman M., Opmeer B.C., Bossuyt P., Eijkemans M.J., Mol B.W., Broekmans F.J., IMPORT Study G.R.O.U.P. and Ng E.H.Y., Added value of ovarian reserve testing on patient characteristics in the prediction of ovarian response and ongoing pregnancy: an individual patient data approach., Human Reproduction Update. 2013, 19(1): 26-36.
Broer S.L., Dolleman M., van Disseldorp J., Broeze K.A., Opmeer B.C., Bossuyt P.M., Eijkemans M.J.C., Mol B.W., Broekmans F.J.M., Study Group I.P.D.-.E.X.P.O.R.T. and Ng E.H.Y., Prediction of an excessive response in in vitro fertilization from patient characteristics and ovarian reserve tests and comparison in subgroups: an individual patient data meta-analysis., Fertility and Sterility. Elsevier Inc., 2013, 100(2): 420-429.
Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, Clin Endocrinol (Oxf). 2013.
Chan C.H.Y., Chan C.L.W., Ng E.H.Y., Ho P.C., Lee G.L. and Hui Choi W.H., Incorporating spirituality in psychosocial group intervention for women undergoing in vitro fertilization: A prospective randomized controlled study, Psychology and Psychotherapy. 2012, 85(4): 356-373.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometriosis , 28th European Society of Human Reproduction and Embryology. 2012.
Cheung S.Y.C., Chan C.H. and Ng E.H.Y., Stress and anxiety-depression levels following first-trimester miscarriage: a comparison between women who conceived naturally and women who conceived with assisted reproduction, British Journal of Obstetrics and Gynaecology (An International Journal of Obstetrics and Gynaecology) . 2013, 120: 1090-1097.
Chiu C.N., Lam Y.F.E., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Lee C.L., Glycodelin-A modulates the functions of human macrophages: possible involvement in the maternal-fetal tolerogenic environment, In: American Society for Reproductive Immunology, 12th Congress of the International Society for Immunology Reproduction(ISIR), 28 May-1 June 2013, Boston, USA. USA, American Journal of Reproductive Immunology, 2013, Volume 69, Issue Supplement s2: 42.
Lee C.L., Lam E.Y., Lam K.K., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates interleukin-6 secretion from human monocytes and macrophages through L-selectin and extracellular signal-regulated kinases pathway., Journal of Biological Chemistry. 2012, 287(44): 36999-37009.
Lee C.Y.L., PENG Q., Fong S.W., CHEN C.H., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways, PLoS One. 2012, 7(9): e45633.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Luteal phase support does not improve the clinical pregnancy rate of natural cycle frozen-thawed embryo transfer: a retrospective analysis, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 169(1): 50-53.
Lee V.C.Y., Ng E.H.Y. and Ho P.C., Male infertility, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Sept-Oct: 213-220.
Li J., Wang W., Liang H., Dong H., Li Y., Ng E.H.Y. and Wu X., Biophysical Characteristics of Meridians and Acupoints: A Systematic Review, Evidence-Based Complementary and Alternative Medicine. 2012, 10.1155: 793841.
Li R.H.W., Ng E.H.Y., Wong B.P.C., Anderson R.A., Ho P.C. and Yeung W.S.B., Correlation between three assay systems for anti-Müllerian hormone (AMH) determination, Journal of Assisted Reproduction and Genetics. 2012, 29: 1443-1446.
Li R.H.W. and Ng E.H.Y., Management of anovulatory infertility, Best Practice & Research Clinical Obstetrics & Gynaecology. 2012, 26: 757-768.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of Baseline Antral Follicle Count and Anti-Mullerian Hormone in Prediction of Cumulative Live Birth in the First In Vitro Fertilisation Cycle: A Retrospective Cohort Analysis, PLos One. 2013, 8(4): e61095.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate may contribute to contraceptive action by its effects on tubal function, The European Journal of Contraception and Reproductive Health Care. 2013, 18 (Supplement 1): S193-S194.
Ng E.H.Y., 中醫生殖軸理論在多囊卵巢綜合征和輔助生殖中的轉化應用與發展”in collaboration with the Heilongjiang University of Chinese Medicine being conferred a First Class Award under the category of the Scientific and Technological Progress Award 2011., 第四屆中國針灸學會科學技術獎一等獎--“女性生殖障礙的針刺療效機制” . 2013.
O W.S., Li R.H.W., Liao S., Ho J.C.M., Ng E.H.Y., Yeung W.S.B., Cheung A.N.Y. and Tang F., 36. Adrenomedullin as a biomarker for tubal ectopic pregnancy - new evidence from adrenomedullin function in the nasal ciliary epithelium., Society for Reproduction and Fertility Abstract Series July 2012, #O019. 2012, 16.
O W.S., Li R.H.W., Liao S., Ho J.C.M., Ng E.H.Y., Yeung W.S.B., Cheung A.N.Y. and Tang F., Adrenomedullin as a biomarker for tubal ectopic pregnancy – new evidence from adrenomedullin function in the nasal ciliary epithelium. Society for Reproduction and fertility, Edinburgh, United Kingdom, #O019, July 2012.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100(2): 459-463.
XIANG L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Nanoparticle tracking of a slow cycling stem-like subpopulation in human endometrium., 11th International Stem Cell Society. 2013.
Yeung T.W.Y., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized double-blinded placebo-controlled trial on the effect of dehydroepiandrosterone for 16 weeks on ovarian response markers in women with primary ovarian insufficiency, Journal of Clinical Endocrinology and Metabolism. 2013, 98(1): 380-388.


Researcher : Ng TY

Project Title:A propective randomised controlled trial: prevention of lymphedema by omentoplasty after pelvic lymphadenectomy
Investigator(s):Ng TY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2001




Researcher : Ngai CSW

Project Title:Vaginal misoprostol for first trimester termination of pregnancy prior to 9 weeks of gestation
Investigator(s):Ngai CSW, Tang FOS, Chan YM, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:05/1999


Project Title:Cervical assessment in prediction of preterm labour: is three-dimensional ultrasonography a better choice?
Investigator(s):Ngai CSW, Lao TTH, Chen M, Leung KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Multiple pregnancy and gestational diabetes: a physiological response or a pathologic condition?
Investigator(s):Ngai CSW, Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The XIXth Asian and Oceanic Congress of Obstetrics & Gynaecology Should We Screen Sexually Transmitted Diseases for Women Requesting for Termination of Pregnancy?
Investigator(s):Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2005




Researcher : Ngan HYS

Project Title:High dose cis-platinum and cyclophosphamide vs taxol in ovarian cancer
Investigator(s):Ngan HYS, Wong RLC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:07/1994


Project Title:Functional role of DNp73-C35 interaction in chemo-resistance of ovarian cancer.
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011


Project Title:Functional characterization and clinical significance of DNp73-C35 in ovarian cancer
Investigator(s):Ngan HYS, Chan KKL, Cheung ANY, Leung THY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2011


Project Title:Characterization of tumor initiating cell population expressing CD55 in cervical cancer.
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012


Project Title:Clinical significance and application of HPV-related microRNAs in cervical pre-maglinant lesions and cancer
Investigator(s):Ngan HYS, Liu S, Ng EKO, Cheung ANY, Chan KKL, Kwong A
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013


Project Title:Roles of CD55(+) population and HPV viral proteins on tumor progression in cervical cancer cells
Investigator(s):Ngan HYS, Leung THY, Cheung ANY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


List of Research Outputs

Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFkB activity is associated with the aggressiveness of ovarian cancers, 17th Research Postgraduate Symposium . 2012.
Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFkB activity is associated with the aggressiveness of ovarian cancers, 19th Hong Kong International Cancer Congress . 2012.
Cai C., Chan D.W. and Ngan H.Y.S., Increased activation of TAK1/NFB activity is associated with the aggressiveness of ovarian cancers, European Association of Cancer Research (EACR) 2012 Congress, Barcelona 7 -10 July 2012.
Chan D.W., Kwan H.T. and Ngan H.Y.S., AMPK activators inhibit cervical cancer cell growth through inhibition of Dvl3 mediated Wnt/b-catenin signaling, 2012 Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia. 2012.
Chan D.W., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer, Oncotarget. 2012, 3.
Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Chan D.W. and Ngan H.Y.S., The AMP-activated protein kinase gamma-2 (AMPK-g2) subunit acts as a modifier of AMPK activity in ovarian cancer cells, CSH Asia / ICMS Joint Conference on Tumor Microenvironment, Suzhou Dushu Lake Conference Center No.299 Qiyue Road SIP/ Suzhou, Jiangsu Province, China. 2012.
Chan D.W., Cai C., Yung M.H. and Ngan H.Y.S., The AMPK/TAK1 signaling axis is indispensable for controlling ovarian cancer cell metabolism and omental metastasis, COLD SPRING HARBOR ASIA CONFERENCES: Metabolism, Obesity and Obesity-associated Diseases. Suzhou Dushu Lake Conference Center May 20-24, 2013. Suzhou, Jiangsu Province, China.. Suzhou, Jiangsu Province, China., 2013.
Chan D.W. and Ngan H.Y.S., The prognostic and therapeutic potential of AMP-activated protein kinase in ovarian cancer, ASGO 2nd International Workshop on Gynecologic Oncology September 28 (Fri), 2012 Kyoto Tokyu Hotel, Japan . 2012.
Chan R.W., Mak A.S., Yeung W.S., Lee K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S., Human female reproductive tract epithelial cell culture, In: Siu MK, Wong ES, Kong DS, Chan HY, Jiang L, Wong OG, Lam EW, Chan KK, Ngan HY, Le XF, Cheung AN, Methods Mol Biol. 2012.
Chan R.W.S., Mak A.S.C., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S.T., Human Female Reproductive Tract Epithelial Cell Culture. In: Epithelial Cell Culture Protocols: Second Edition, Methods in Molecular Biology, vol. 945, Chapter 21., Scott H. Randell and M. Leslie Fulcher . 2013, 945: Ch21.
Cheung A.N.Y. and Ngan H.Y.S., Fallopian tube cancer, In: Cheung AN, Ngan HY, Clinical Gynecology, 2nd Edition (In press). Cambridge University Press, 2013.
Cheung S.Y.C., Liu S., Ip P.P.C., Cheung A.N.Y. and Ngan H.Y.S., GENETIC AMPLIFICATION OF PIK3CA IN VULVAR SQUAMOUS CELL CARCINOMA, Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
Garland S.M., Bhatla N. and Ngan H.Y.S., Cervical Cancer Burden and Prevention Strategies: Asia Oceania Perspective, Cancer Epidemiol Biomarkers Prev, 21(9):1414-22. 2012.
Kwan H.T., Chan D.W., Cai C., Mak S.L., Yung M.H., Leung T.H.Y., Wong G.W., Cheung A.N.Y. and Ngan H.Y.S., AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity, PLoS ONE. 2013, 8: e53597.
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., MicroRNA-135a regulates cervical cancer transformation and progression through ß-catenin via a SIAH1-dependent ubiquitin-proteosomal pathway, The 19th Hong Kong International Cancer Congress. 2012.
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., Role of microRNA-135a in cervical cancer transformation and development., The 17th Research Postgraduate Symposium. 2012.
LEUNG T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN), 28th International Papillomavirus Conference, San Juan, Puerto Rico, Nov 30 – Dec 6, 2012. . 2012.
Leung T.W., Liu S., Chan A.N.H., Cheung A.N.Y. and Ngan H.Y.S., EXPRESSION OF NOTCH 1 PROTEIN IN CERVICAL CANCER AND CERVICAL PREMALIGNANT LESIONS AND ITS CORRELATION WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION AND CLINICAL PARAMETERS , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
Li C., Liu V.W.S., Chiu P.M., Chan D.W. and Ngan H.Y.S., Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications, BMC Cancer. BioMed Central, 2012, 12: 357.
Liu S., Ng E.K.O., Leung C.Y., Cheung A.N.Y., Kwong A. and Ngan H.Y.S., ALTERED MICRORNA EXPRESSION ASSOCIATED WITH HUMAN PAPILLOMAVIRUS (HPV) INFECTION IN CERVICAL CANCER , Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia, Hong Kong. 2012.
Liu S., Ng E.K.O., Leung C.Y., Cheung A.N.Y., Kwong A. and Ngan H.Y.S., Aberrant miRNA expressions associated with Human Papillomavirus (HPV) infection contribute to cervical carcinogenesis , 28th International Papillomavirus Conference, Puerto Rico, Nov.30-Dec. 6, 2012.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of MicroRNA-199b-5p is associated with chemoresistance via JAG1-Notch1 in human epithelial ovarian cancer, 17th Research Postgraduate Symposium . 2012.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of MicroRNA-199b-5p is associated with chemoresistance via JAG1-Notch1 in human epithelial ovarian cancer, 19th Hong Kong International Cancer Congress . 2012.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of miR-199b-5p is associated with chemoresistance via Jagged1 in human ovarian cancer, European Association of Cancer Research (EACR) 2012 Congress, Barcelona 7 -10 July 2012.
Mak C.Y., Lee L., Siu K.Y., Wong G.W., Lu X., Ngan H.Y.S., Wong E.S. and Cheung A.N.Y., Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation , Carcinogenesis. 2013, June 2013.
Mak S.L., Chan D.W. and Ngan H.Y.S., The Upregulation of miR-141 Confers Anoikis Resistance through Targeting KLF12 in Ovarian Cancer Cells , 19th Hong Kong International Cancer Congress . 2012.
Mak S.L., Chan D.W. and Ngan H.Y.S., The upregulation of miR-141 confers anoikis resistance through targeting KLF12 in ovarian cancer cells, microRNA: Targets and Tools for Therapeutic Development. 3rd March - 5th March. Boston Marriott Cambridge, Cambridge, MA, USA. 2013.
Mak S.L., Chan D.W. and Ngan H.Y.S., miR-141 confers anoikis resistance of ovarian cancer cells by targeting KLF12, 17th Research Postgraduate Symposium . 2012.
Ngan H.Y.S., "Role of Tumour Markers in Gynaecological Cancers” & “Role of Lymphadenectomy in Endometrial Cancers”, National Gynae-Oncology Conference 2012, Kuala Lumpur, Malaysia, September 21. 2012.
Ngan H.Y.S., Diagnosis and Management of uterine sarcoma, The 2012 General Assembly and Annual Meeting of Asian GOG, , Bangkok, Thailand, November 17-18. 2012.
Ngan H.Y.S., Editorial Board Member - Journal of Clinical Oncology (Chinese Edition) since 2000. 2013.
Ngan H.Y.S., Editorial Board Member - Journal of Medical Association of Thailand. 2013.
Ngan H.Y.S., Editorial Board Member - Journal of Obstetrics and Gynaecology Research since 1997. 2013.
Ngan H.Y.S., Editorial Board Member - Journal of Paediatrics, Gynaecology and Obstetrics since 1997. 2013.
Ngan H.Y.S., Editorial Board Member - The Hong Kong Medical Journal. 2013.
Ngan H.Y.S., Editorial Board Member of 实用婦產科雜誌(編委). 2013.
Ngan H.Y.S., Editorial Member - 中華婦產科雜誌. 2013.
Ngan H.Y.S., Editorial Member - 國際婦產科學雜誌第七屆編輯委員會. 2013.
Ngan H.Y.S., Fertility Preservation in Gynecologic Malignancies – Present Issues and Future Perspectives – Cervical Cancer, The 2nd International Workshop on Gynecologic Oncology of Asian Society of Gynecologica Oncology (ASGO) - AOFOG Oncology Committee Workshop, Kyoto, Japan, September 29. 2012.
Ngan H.Y.S., HPV epidemiology an and the burden of cervical disease in AP (Plenary Lecture), EXCCEL Hong Kong Expert Speakers’ Forum, Chairperson & Invited Speaker, Hong Kong, 16 July. 2012.
Ngan H.Y.S., HPV infection and the progression of infection to cervical cancer, Malaysian Seminar in Cervical Cancer Prevention, Kuala Lumpur, Malaysia, September 20. 2012.
Ngan H.Y.S., HPV疫苗: 長效研究報告及國家注射計劃的成果, 第十屆粵港澳台預防醫學學術會議 , Macau, May 25. 2013.
Ngan H.Y.S., Laparoscopic radical hysterectomy, 2012 Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia (AOGIN), Hong Kong, July 13. 2012.
Ngan H.Y.S., Lecture-“HPV Vaccination in Men”, Panelist: “Safety of HPV Vaccine”, , The 3rd National Conference – Asia Oceania Research Organization on Genital Infection & Neoplasia (AOGIN), Chennai, India, November 2-4. 2012.
Ngan H.Y.S., Management of High Risk GTN and PSTT/ETT, 14th Biennial Meeting of International Gynecologic Cancer Society (IGCS), Vancouver, Canada, October 13-16. 2012.
Ngan H.Y.S., Molecular targeted therapy in ovarian cancer , Hong Kong Pathology Forum 2013, January 26. 2013.
Ngan H.Y.S., President Lecture: Cervical Cancer Prevention – Double Challenges, 2012 Conference of Asia Oceania Research Organisation on Genital Infections and Neoplasia (AOGIN), Hong Kong, July 14. 2012.
Ngan H.Y.S., Robotic Radical Hysterectomy and Lymphadenectomy in Cervical Cancer, Gynaecologic Cancer Conference, Guangzhou, China, November 22. 2012.
Ngan H.Y.S., Robotic Surgery in Endometrial Cancer, 10th Nationwide Cervical precancerous Lesion & Cervical Cancer Seminars on Topical issues, Beijing, China, April 21. 2013.
Ngan H.Y.S., Robotic radical hysterectomy and lymphadenecotomy in cervical cancer, 2012 Meeting of China Society of Gynecological Oncologists (CSGO2012), Beijing, 27 October 2012. 2012.
Ngan H.Y.S., Session of Gestational Trophoblastic neoplasia - “Have we got the ideal staging yet?”, XX FIGO World Congress, 7-12 October. 2012.
Ngan H.Y.S., Surgical treatment with a view to fertility preservation, The International Conference on Preservation of Fertility in Cancer Patient 2013, Hong Kong, February 2. 2013.
Ngan H.Y.S., Targeted Therapy for Ovarian Cancer Management , Macau Oncology Association Ovarian Cancer Symposium 2013, Macau, May 23. 2013.
Ngan H.Y.S., The need for educating the public about HPV and cervical cancer prevention: Point Key Message for Cervical Cancer Awareness, 65. Asia Oceania Research Organization on Genital Infection & Neoplasia (AOGIN) 2013 Interim Conference, Kunming, China, April 25-28. 2013.
Ngan H.Y.S., Kohorn E.I., Cole L.A., Kurman R.J., Kim S.J., Lurain J.R., Seckl M.J., Sasaki S. and Soper J.T., Trophoblastic disease, International Journal of Gynecology and Obstetrics, 2012 October. 2012, 119 (Suppl 2): S130-S136.
Siu K.Y., Kong D.S., Chan H.Y., Wong E.S.Y., Ip P.P.C., Jiang L., Ngan H.Y.S., Le X.F. and Cheung A.N.Y., Paradoxical impact of two folate receptors, FRα and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome, In: Siu MK, Kong DS, Chan HY, Wong ES, Ip PP, Jiang L, Ngan HY, Le XF, Cheung AN, PLoS One. 2012.
Siu M.K., Wong E.S.Y., Kong D.S., Chan H.Y., Jiang L., Wong G.W., Lam E.W., Chan K.K., Ngan H.Y.S., Le X.F. and Cheung A.N.Y., Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers, In: Siu MK, Wong ES, Kong DS, Chan HY, Jiang L, Wong OG, Lam EW, Chan KK, Ngan HY, Le XF, Cheung AN, Oncogene. 2012.
Tang A., Kondalsamy-Chennakesavan S., Ngan H.Y.S., Zusterzeel P., Quinn M., Carter J., Leung Y. and Obermair A., Prognostic value of elevated preoperative serum CA125 in ovarian tumors of low malignant potential: A multinational collaborative study (ANZGOG0801, Gynecol Oncol, 2012 Jul;. Epub 2012 Feb 24. 2012, 126(1): 36-40.
Wong G.W., Wong I.T., Chu T.C., Ngan H.Y.S. and Cheung A.N.Y., Dysregulation of miR-143 in cervical cancer, AOGIN 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter Melon Extract (BME) used as Natural AMPK Activator in Inhibiting Ovarian Cancer Cells Growth, 17th Research Postgraduate Symposium. Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong.. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter Melon Extract (BME) used as Natural AMPK Activator in Inhibiting Ovarian Cancer Cells Growth, 19th Hong Kong International Cancer Congress Hong Kong Academy of Medicine, 99 Wong Chuk Hang Road, Aberdeen, Hong Kong.. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter melon extract (BME) used as natural AMPK activator in inhibiting ovarian cancer cells growth , CSH Asia / ICMS Joint Conference on Tumor Microenvironment Suzhou Dushu Lake Conference Center No.299 Qiyue Road SIP/ Suzhou, Jiangsu Province, China. 2012.
Zhang P., Liu S. and Ngan H.Y.S., TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells, In: Wael El-Rifai, PLoS One. 2012, 7(8).


Researcher : Ngu SF

Project Title:Vaginal microflora in women who use ring pessary for pelvic organ prolapse
Investigator(s):Ngu SF, Seneviratne CJ, Ma WSP, Cheung VYT, Pun TC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2013


List of Research Outputs

Cheung K.W., Ngu S.F. and Lee C.P., Fetal Fibronectin Test On Chinese Women With Symptoms Of Preterm Labour: A Pilot Study, Hong Kong Medical Journal. 2013.
Chia C.F., Lai J.H.Y., Cheung P.K., Kwong L.T., Lau F.P.M., Leung K.H., Leung M.T., Wong F.C.H. and Ngu S.F., Dysmenorrhoea Among Hong Kong University Students: Prevalence, Impact, And Management, Hong Kong Medical Journal. 2013.
Ngai F.W. and Ngu S.F., Family Sense Of Coherence And Quality Of Life, Qual Life Res. 2012.
Ngai F.W. and Ngu S.F., Family Sense of Coherence and Depressive Symptoms among Childbearing Couples, XI World Congress of Perinatal Medicine. 2013.
Ngai F.W. and Ngu S.F., Family Sense of Coherence and Family and Marital Functioning during Pregnancy, The Asian Conference on Arts and Humanities 2013.
Ngai F.W. and Ngu S.F., Quality of Life during the Transition to Parenthood, International Interdisciplinary Conference. 2013.
Ngu S.F., HPV and Pregnancy, 2012 Conference of Asia Oceania Research Organisation of Genital Infections and Neoplasia (AOGIN 2012). 2012.
Ngu S.F., Management of ovarian cyst complicating pregnancy, 10th Asian Federation of Societies for Ultrasound in Medicine and Biology (AFSUMB) Workshop. 2012.
Ngu S.F., Ovarian cyst complicating pregnancy, Postgraduate Study Day, Department of Obstetrics and Gynaecology, Queen Mary Hospital. 2012.
Ngu S.F., Ko K.Y.J. and Cheung V.Y.T., Value of human chorionic gonadotropin levels in diagnosing cervical ectopic pregnancy, Acta Obstet Gynecol Scand. 2012.
Pun T.C., Ngu S.F., Seto T.Y.M. and Cheung V.Y.T., Second Trimester Termination of Pregnancy After Previous Classical Caesarean Section for Uterine Fibroid, RCOG World Congress 2013, Liverpool UK. 2013.
Seto T.Y.M., Ngu S.F., Cheung V.Y.T. and Pun T.C., Second Trimester Medical Abortion In A Woman With Prior Classical Caesarean Section And A Uterine Leiomyoma - A Case Report., Eur J Contracept Reprod Health Care. 2013.


Researcher : Ong CYT

Project Title:To determine the correlation of changes in maternal levels of pregnancy-associated plasma protein A (PAPP-A) and free [beta] human chorionic gonadotrophin (F[beta]-hCG) with placental development and fetal outcomes
Investigator(s):Ong CYT, Lao TTH, Leung WC, Leung KY, Lam HSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:First trimester prediction of fetal α-thalassaemia-1 with maternal serum markers, nuchal translucency measurement and three dimentional ultrasound measurement of placental volume
Investigator(s):Ong CYT, Chen M, Leung KY, Tang MHY, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Maternal serum level of ADAM 12 as an early marker of trisomy 21, trisomy 13 and trisomy 18
Investigator(s):Ong CYT, Lee CP, Lau ETK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2007




Researcher : PENG Q

List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
Lee C.Y.L., PENG Q., Fong S.W., CHEN C.H., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways, PLoS One. 2012, 7(9): e45633.


Researcher : Pang RTK

Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang RTK, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007


List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., The estrogen-regulated Let-7a plays a pivotal role during blastocyst activation via its effect on Vav3, The 7th International Huaxia Congress of Endocrinology, Hong Kong. 2012.
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., MicroRNA-135a regulates cervical cancer transformation and progression through ß-catenin via a SIAH1-dependent ubiquitin-proteosomal pathway, The 19th Hong Kong International Cancer Congress. 2012.
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., Role of microRNA-135a in cervical cancer transformation and development., The 17th Research Postgraduate Symposium. 2012.
Lam K.W., Pang R.T.K., Lee C.Y.L., Koistinen H., Seppala M., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line., Placenta. Elsevier, 2012, 33: 750-2.
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.


Researcher : Pun TC

List of Research Outputs

Pun T.C., Ngu S.F., Seto T.Y.M. and Cheung V.Y.T., Second Trimester Termination of Pregnancy After Previous Classical Caesarean Section for Uterine Fibroid, RCOG World Congress 2013, Liverpool UK. 2013.
Seto T.Y.M., Ngu S.F., Cheung V.Y.T. and Pun T.C., Second Trimester Medical Abortion In A Woman With Prior Classical Caesarean Section And A Uterine Leiomyoma - A Case Report., Eur J Contracept Reprod Health Care. 2013.


Researcher : Seto TYM

List of Research Outputs

Pun T.C., Ngu S.F., Seto T.Y.M. and Cheung V.Y.T., Second Trimester Termination of Pregnancy After Previous Classical Caesarean Section for Uterine Fibroid, RCOG World Congress 2013, Liverpool UK. 2013.
Seto T.Y.M., Ngu S.F., Cheung V.Y.T. and Pun T.C., Second Trimester Medical Abortion In A Woman With Prior Classical Caesarean Section And A Uterine Leiomyoma - A Case Report., Eur J Contracept Reprod Health Care. 2013.


Researcher : Shek NWM

List of Research Outputs

Tang M.H.Y., Lau E.T.K., Tan T.Y., Chung B.H.Y. and Shek N.W.M., Prenatal Diagnosis of Agenesis of the Corpus Callosum and Cerebellar Vermian Hypoplasia Associated with a Microdeletion on Chromosome 1p32: Decision Minor revision, Case Reports in Perinatal Medicine. 2013, 2;1-2: 39-45.


Researcher : Siu KY

Project Title:Effects of folate and folate receptor on ovarian and endometrial cancer: an in vitro study
Investigator(s):Siu KY, Cheung ANY
Department:Pathology
Source(s) of Funding:American Institute for Cancer Research (AICR) - General Award
Start Date:07/2006


Project Title:p21-activated kinase 4: a prognostic and therapeutic target for ovarian carcinoma?
Investigator(s):Siu KY, Cheung ANY, Ngan HYS
Department:Pathology
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2007


List of Research Outputs

Siu K.Y., Kong D.S., Chan H.Y., Wong E.S.Y., Ip P.P.C., Jiang L., Ngan H.Y.S., Le X.F. and Cheung A.N.Y., Paradoxical impact of two folate receptors, FRα and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome, In: Siu MK, Kong DS, Chan HY, Wong ES, Ip PP, Jiang L, Ngan HY, Le XF, Cheung AN, PLoS One. 2012.


Researcher : Tam KF

List of Research Outputs

TANG K.S., Kwong A., Tam K.F. and Wong A.S.T., BRCA1 inactivation induces autophagy as an adaptive survival mechanism in breast and ovarian cancer cells, 7th International Huaxia Congress of Endocrinology, Hong Kong (Abstract No. 130). 2012.


Researcher : Tang FOS

Project Title:A prospective randomized comparison of sublingual and vaginal misoprostol in termination of pregnancy in the second trimester
Investigator(s):Tang FOS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:10/2000




Researcher : Tang GWK

Project Title:A cross sectional health care study of Chinese perimenopausal women in Hong Kong
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:01/1993


Project Title:A double-blind randomized placebo-controlled clinical trial on the effects of Chinese medicine formula (Erxian Decoction) on menopausal symptoms
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Liu Hao Tsing Education Foundation Limited & Private Outside Practice Fund
Start Date:04/2009
Completion Date:12/2012


List of Research Outputs

Tang G.W.K., Reviewer for "The Hong Kong Practitioner, 2013.
Tang G.W.K., 深化深港合作樹立改革典範 February 22, 2013, 智經研究中心, 大珠三角商務委員會. 2013.


Researcher : Tang MHY

List of Research Outputs

Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762.
Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Kan A.S.Y., Lee C.P., Leung K.Y., Chan C.P., Tang M.H.Y. and Chan V.H.Y., Outcome of twin pregnancy after amniocentesis, Journal of Obstetrics and Gynaecology Research. 2012, 38(2): 376-382.
Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH evaluation for prenatal diagnosis in Hong Kong, Poster presentation (P1-9) in 16th International Conference on Prenatal Diagnosis and Therapy, 3-6 June, Miami, USA. Prenat Diagn 2012;32(Supp. 1):S1 . 2012.
Tang M.H.Y., Lau E.T.K., Tan T.Y., Chung B.H.Y. and Shek N.W.M., Prenatal Diagnosis of Agenesis of the Corpus Callosum and Cerebellar Vermian Hypoplasia Associated with a Microdeletion on Chromosome 1p32: Decision Minor revision, Case Reports in Perinatal Medicine. 2013, 2;1-2: 39-45.
Tsang J.S., Tong D.K.H., Chung B.H.Y., Tang M.H.Y., Lau E.T.K., Chan G.C.F. and Law S.Y.K., Alport's syndrome: case of a giant esophageal tumor [Doi:10.1007/s10388-012-0355-3], Esophagus. Springer, 2013, 10: 114-117.


Researcher : Tang WF

List of Research Outputs

Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762.
Kan A.S.Y., Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C., Chan Y.K. and Tang M.H.Y., Array CGH testing in Prenatal Diagnosis: A Promising New Service with Improved Diagnostic Yield and Shortened Reporting Time, Electronic presentation (Abstract 904) in Hospital Authority Convention 2012, 7-8 May, Hong Kong. . 2012.
Lau E.T., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH evaluation for prenatal diagnosis in Hong Kong, Poster presentation (P1-9) in 16th International Conference on Prenatal Diagnosis and Therapy, 3-6 June, Miami, USA. Prenat Diagn 2012;32(Supp. 1):S1 . 2012.
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318.


Researcher : Wong BPC

List of Research Outputs

Li R.H.W., Ng E.H.Y., Wong B.P.C., Anderson R.A., Ho P.C. and Yeung W.S.B., Correlation between three assay systems for anti-Müllerian hormone (AMH) determination, Journal of Assisted Reproduction and Genetics. 2012, 29: 1443-1446.


Researcher : XIANG L

List of Research Outputs

XIANG L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Nanoparticle tracking of a slow cycling stem-like subpopulation in human endometrium., 11th International Stem Cell Society. 2013.


Researcher : YE T

List of Research Outputs

LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., MicroRNA-135a regulates cervical cancer transformation and progression through ß-catenin via a SIAH1-dependent ubiquitin-proteosomal pathway, The 19th Hong Kong International Cancer Congress. 2012.
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., Role of microRNA-135a in cervical cancer transformation and development., The 17th Research Postgraduate Symposium. 2012.
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.


Researcher : Yeung TWY

List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, Clin Endocrinol (Oxf). 2013.
Yeung T.W.Y., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized double-blinded placebo-controlled trial on the effect of dehydroepiandrosterone for 16 weeks on ovarian response markers in women with primary ovarian insufficiency, Journal of Clinical Endocrinology and Metabolism. 2013, 98(1): 380-388.


Researcher : Yeung WSB

Project Title:Characterization of Stem/Progenitor Cells in Human Endometriosis
Investigator(s):Yeung WSB, Chan RWS, Lee CKF, Luk JMC, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010
Completion Date:12/2012


Project Title:Role of microRNA let-7 in implantation of mouse blastocysts
Investigator(s):Yeung WSB, Lee CKF, Liu W, Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2011


Project Title:Control of human extravillous cytotrophoblast invasion by adrenomedullin
Investigator(s):Yeung WSB, Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2011
Completion Date:02/2013


Project Title:MicroRNA-135a induction transforms normal human papillomarvirus infected cervical cells into cells with cancer stem cell-like properties.
Investigator(s):Yeung WSB, Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


Project Title:12th International Conference on Preimplantation Genetic Diagnosis; Validation of a preimplantation genetic diagnosis protocol for double factor- alpha-thalassemia and reciprocal translocation
Investigator(s):Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2013


List of Research Outputs

CHEN C.H., Lee C.Y.L., HOU Y.C.D., Fong S.W., PENG Q., Pang R.T.K., Chiu C.N., Ho P.C., Lee C.K.F. and Yeung W.S.B., Study of transforming growth factor alpha for the maintenance of human embryonic stem cells., Cell Tissue Res.. 2012, 350(2): 289-303.
CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., The estrogen-regulated Let-7a plays a pivotal role during blastocyst activation via its effect on Vav3, The 7th International Huaxia Congress of Endocrinology, Hong Kong. 2012.
Chan R.W.S., Mak A.S.C., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S.T., Human Female Reproductive Tract Epithelial Cell Culture. In: Epithelial Cell Culture Protocols: Second Edition, Methods in Molecular Biology, vol. 945, Chapter 21., Scott H. Randell and M. Leslie Fulcher . 2013, 945: Ch21.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometriosis , 28th European Society of Human Reproduction and Embryology. 2012.
Chiu C.N., Lam Y.F.E., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Lee C.L., Glycodelin-A modulates the functions of human macrophages: possible involvement in the maternal-fetal tolerogenic environment, In: American Society for Reproductive Immunology, 12th Congress of the International Society for Immunology Reproduction(ISIR), 28 May-1 June 2013, Boston, USA. USA, American Journal of Reproductive Immunology, 2013, Volume 69, Issue Supplement s2: 42.
Chiu C.N., Lee C.L., Zhao W., Huang W., Lam K.W., Ho P.C. and Yeung W.S.B., Identification of sialyl-Lewis(x) (SLEX)-binding protein on human spermatozoa and its role on sperm-zona pellucida interaction, In: European Society of Human Reproduction and Embryology, 28th Annual Meeting of the European Society of Human Reproduction and Embryology . 2012, O-289.
HUANG W., Lee C.L., Lee C.Y.L., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage., Fertil Steril.. 2013, 99(5): 1444-1452.
Huang W., Yeung W.S.B., Ho P.C. and Chiu C.N., Sperm Fucosyltransferase-5 is involved in Spermatozoa-oviductal Epithelial Cell Interaction to Protect Human Spermatozoa from Oxidative Damage, 2013 Glycobiology Gordon Research Conference, Ventura, CA, March 3-8, 2013. .
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., MicroRNA-135a regulates cervical cancer transformation and progression through ß-catenin via a SIAH1-dependent ubiquitin-proteosomal pathway, The 19th Hong Kong International Cancer Congress. 2012.
LEUNG O.N., Pang R.T.K., YE T., Deng W., Tsao G.S.W., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., Role of microRNA-135a in cervical cancer transformation and development., The 17th Research Postgraduate Symposium. 2012.
Lam K.W., Pang R.T.K., Lee C.Y.L., Koistinen H., Seppala M., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line., Placenta. Elsevier, 2012, 33: 750-2.
Lee C.L., Lam E.Y., Lam K.K., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates interleukin-6 secretion from human monocytes and macrophages through L-selectin and extracellular signal-regulated kinases pathway., Journal of Biological Chemistry. 2012, 287(44): 36999-37009.
Lee C.L., Yeung W.S.B. and Chiu C.N., Glycodelin-A stimulates interleukin-6 secretion via L-selectin binding on human monocytes and macrophages, Society for Reproduction and Fertility Annual Meeting 2012. .
Lee C.Y.L., PENG Q., Fong S.W., CHEN C.H., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways, PLoS One. 2012, 7(9): e45633.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Luteal phase support does not improve the clinical pregnancy rate of natural cycle frozen-thawed embryo transfer: a retrospective analysis, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 169(1): 50-53.
Li R.H.W., Ng E.H.Y., Wong B.P.C., Anderson R.A., Ho P.C. and Yeung W.S.B., Correlation between three assay systems for anti-Müllerian hormone (AMH) determination, Journal of Assisted Reproduction and Genetics. 2012, 29: 1443-1446.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of Baseline Antral Follicle Count and Anti-Mullerian Hormone in Prediction of Cumulative Live Birth in the First In Vitro Fertilisation Cycle: A Retrospective Cohort Analysis, PLos One. 2013, 8(4): e61095.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate may contribute to contraceptive action by its effects on tubal function, The European Journal of Contraception and Reproductive Health Care. 2013, 18 (Supplement 1): S193-S194.
O W.S., Li R.H.W., Liao S., Ho J.C.M., Ng E.H.Y., Yeung W.S.B., Cheung A.N.Y. and Tang F., Adrenomedullin as a biomarker for tubal ectopic pregnancy – new evidence from adrenomedullin function in the nasal ciliary epithelium. Society for Reproduction and fertility, Edinburgh, United Kingdom, #O019, July 2012.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100(2): 459-463.
Pang R.T.K., LEUNG O.N., Lee C.L., Lam K.W., YE T., Chiu C.N. and Yeung W.S.B., MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1, BMC Cancer. United Kingdom, Jo Appleford-Cook, 2013, 13: 25.
XIANG L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Nanoparticle tracking of a slow cycling stem-like subpopulation in human endometrium., 11th International Stem Cell Society. 2013.
Yeung W.S.B., Chiu C.N., Dell A.N.N.E., Pang P.O.H.-.C.H.O.O., Khoo K.A.Y.-.H.O.O.I. and Clark G.A.R.Y., Human zona pellucida glycoproteins, their oligosaccharides, and uses thereof (WO/2013/012749), 2013.


Researcher : Yung MH

List of Research Outputs

Chan D.W., Hui W.Y., Cai C., Liu X., Yung M.H., Mak S.L., Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells, PLoS ONE. 2012, 7: e52578.
Chan D.W., Cai C., Yung M.H. and Ngan H.Y.S., The AMPK/TAK1 signaling axis is indispensable for controlling ovarian cancer cell metabolism and omental metastasis, COLD SPRING HARBOR ASIA CONFERENCES: Metabolism, Obesity and Obesity-associated Diseases. Suzhou Dushu Lake Conference Center May 20-24, 2013. Suzhou, Jiangsu Province, China.. Suzhou, Jiangsu Province, China., 2013.
Kwan H.T., Chan D.W., Cai C., Mak S.L., Yung M.H., Leung T.H.Y., Wong G.W., Cheung A.N.Y. and Ngan H.Y.S., AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity, PLoS ONE. 2013, 8: e53597.
Yung M.H. and Chan D.W., BME and MAP30 function as natural AMPK activators in inhibiting ovarian cancer cell growth , 香港大学学者报告会, Department of Biochemistry, Zhijiang University. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter Melon Extract (BME) used as Natural AMPK Activator in Inhibiting Ovarian Cancer Cells Growth, 17th Research Postgraduate Symposium. Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong.. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter Melon Extract (BME) used as Natural AMPK Activator in Inhibiting Ovarian Cancer Cells Growth, 19th Hong Kong International Cancer Congress Hong Kong Academy of Medicine, 99 Wong Chuk Hang Road, Aberdeen, Hong Kong.. 2012.
Yung M.H., Chan D.W. and Ngan H.Y.S., Bitter melon extract (BME) used as natural AMPK activator in inhibiting ovarian cancer cells growth , CSH Asia / ICMS Joint Conference on Tumor Microenvironment Suzhou Dushu Lake Conference Center No.299 Qiyue Road SIP/ Suzhou, Jiangsu Province, China. 2012.


Researcher : Yung SF

Project Title:A randomized comparative trial to compare the efficacy of vaginal misoprostol moistened with 5% acetic acid with dry vaginal misoprostol in the medical management of first trimester silent miscarriage
Investigator(s):Yung SF, Ho PC, Ng EHY, Lee VCY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2011


Project Title:Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps
Investigator(s):Yung SF, Lee CKF, Ng EHY, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013


List of Research Outputs

Yung S.F., "Is this ovarian cyst worrying? - Simple ultrasound rules from the IOTA group", Postgraduate Study Day, Department of Obstetrics and Gynaecology, the University of Hong Kong. 2012.
Yung S.F., Cheung V.Y.T. and Chan G.S.W., Ovarian osteoma mimicking a teratoma on ultrasound, International Journal of Gynecology and Obstetrics. Elsevier Ireland Ltd, 2013, 121(Issue 3): 280-281.


Researcher : Zhang P

List of Research Outputs

Zhang P., Liu S. and Ngan H.Y.S., TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells, In: Wael El-Rifai, PLoS One. 2012, 7(8).


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